Results 151 to 160 of about 149,317 (350)

P1-396 Hepatitis B virus (HBV) infection in relation to consistent condom use: a population-based study in Peru [PDF]

open access: bronze, 2011
Antonio Bernabé‐Ortiz   +5 more
openalex   +1 more source

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

open access: yesAdvanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma   +10 more
wiley   +1 more source

Sexual behaviour of secondary-school students in Slovenia in the year 2004

open access: yesZdravniški Vestnik, 2006
Background: In order the aim to evaluate the risk-taking behaviour, a representative study on sexual behaviour of secondary-school students in Slovenia was performed.Methods: In the spring of 2004, 2380 1st and 3rd grade students from 48 randomly ...
Bojana Pinter   +18 more
doaj  

Biomimetic Organic Nanozyme as Tumor Vaccines for Targeted Suppression of Ammonia‐Induced T Lymphocyte Death to Augment Breast Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The organic nanozyme IR‐IHpd, which has NIR‐PDT and POD‐like activity, is designed for continuous ROS generation. It is co‐encapsulated with CB‐839 and coated with DC membranes to simultaneously target tumors and T cells. Under NIR irradiation, immunogenic cell death is activated. Concurrently, CB‐839 suppresses ammonia‐induced T lymphocyte death (AITD)
Meng Suo   +7 more
wiley   +1 more source

Sexual risk behaviors in Brazilian adolescents and young women

open access: yesDST, 2018
Introduction: Risky sexual behaviors among adolescents can result in high rates of sexually transmitted infections and unwanted pregnancies. Objective: To estimate the prevalence and to identify sociodemographic factors associated with early start of ...
Caroline Ferreira dos Anjos   +3 more
doaj  

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

open access: yesAdvanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang   +11 more
wiley   +1 more source

Factors associated to inconsistent condom use among sex workers [PDF]

open access: diamond, 2019
Rosilane de Lima Brito Magalhães   +5 more
openalex   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang   +7 more
wiley   +1 more source

Multisectoral Convergence of Food, Nutrition and Sanitation Programs for Child Health: Evidence From Country‐Level Programs in India

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper underscores the critical role of multisectoral convergence in enhancing child health, particularly in addressing anemia, a micronutrient deficiency linked to both diet and sanitation. We explore how the integration of nationwide food and nutrition programs with sanitation initiatives impacts anemia in Indian children under three ...
Soumya Gupta, Payal Seth, Prabhu Pingali
wiley   +1 more source

Home - About - Disclaimer - Privacy