Results 91 to 100 of about 725,143 (289)

Desenho em série com meninas que apresentam comportamento oposicionista desafiante em sala de aula [PDF]

, 2015
Este estudio investigó las correlaciones entre la participación en sesiones terapéuticas de dibujo en serie, no dirigido, y la presencia o ausencia de mejoría en el comportamiento oposicionista desafiante (COD) de cinco niñas, de ocho a diez años de edad,
Boone-Salles, Andréia Mansk
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Evaluation of Aggression and Socioeconomic Factors associated it, Among Preschool Children

Journal of Holistic Nursing and Midwifery, 2016
Introduction: Childhood aggression is a major health problem throughout the world, particularly in recent years. Aggression in the preschool years, when the child starts extensive interaction with age group, becomes an important issue.
Somayeh Shirkosh, Mahshid Mirzaei, Rasool Tabari, Ehsan KazemnejadLeili, Maryam Rostami   +4 more
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Low-Dose Risperidone-Induced Facial Edema in a Child with Conduct Disorder

Psychiatry and Behavioral Sciences, 2018
Risperidone, a benzisoxazole derivate, is a widely prescribed antipsychotic agent that binds with high affinity to dopamine D2, serotonin type 2 (5-HT2) and α1-adrenergic receptors, and causes antagonism at these receptor sites. Although risperidone
Hamza Ayaydin, Sermin Bilgen Ulgar
doaj   +1 more source

PTSD from Childhood Trauma as a Precursor to Attachment Issues [PDF]

, 2016
The past 20 years have been turbulent regarding Reactive Attachment Disorder (RAD), with conflicting research about its causes, effects, treatment, and prognosis. The current diagnostic criteria in the DSM-5 fails to adequately address this disorder.
Owen, Christy
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Empathy in Youths with Conduct Disorder and Callous-Unemotional Traits

Neural Plasticity, 2019
Previous studies indicated that a lack of empathy could be considered the core feature of callous-unemotional (CU) traits in children and adolescents.
Annarita Milone, Luca Cerniglia, Chiara Cristofani, Emanuela Inguaggiato, Valentina Levantini, Gabriele Masi, Marinella Paciello, Francesca Simone, Pietro Muratori   +8 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Differential neuropsychological functioning between adolescents with attention-deficit/hyperactivity disorder with and without conduct disorder

Journal of the Formosan Medical Association, 2017
Background/Purpose: This study aimed to evaluate neuropsychological functioning of attention-deficit/hyperactivity disorder (ADHD) with and without comorbidities of oppositional defiant disorder (ODD) and/or conduct disorder (CD) and the mediation ...
Yu-Ju Lin, Susan Shur-Fen Gau
doaj   +1 more source