Results 101 to 110 of about 10,805,600 (327)

Empathy in Youths with Conduct Disorder and Callous-Unemotional Traits

Neural Plasticity, 2019
Previous studies indicated that a lack of empathy could be considered the core feature of callous-unemotional (CU) traits in children and adolescents.
Annarita Milone, Luca Cerniglia, Chiara Cristofani, Emanuela Inguaggiato, Valentina Levantini, Gabriele Masi, Marinella Paciello, Francesca Simone, Pietro Muratori   +8 more
doaj   +1 more source

Low-Dose Risperidone-Induced Facial Edema in a Child with Conduct Disorder

Psychiatry and Behavioral Sciences, 2018
Risperidone, a benzisoxazole derivate, is a widely prescribed antipsychotic agent that binds with high affinity to dopamine D2, serotonin type 2 (5-HT2) and α1-adrenergic receptors, and causes antagonism at these receptor sites. Although risperidone
Hamza Ayaydin, Sermin Bilgen Ulgar
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Evaluation of Aggression and Socioeconomic Factors associated it, Among Preschool Children

Journal of Holistic Nursing and Midwifery, 2016
Introduction: Childhood aggression is a major health problem throughout the world, particularly in recent years. Aggression in the preschool years, when the child starts extensive interaction with age group, becomes an important issue.
Somayeh Shirkosh, Mahshid Mirzaei, Rasool Tabari, Ehsan KazemnejadLeili, Maryam Rostami   +4 more
doaj  

Agile Method in Social Work with Children and Adolescents Exhibiting Conduct Disorder and Antisocial Behaviour: Case of Kidsköpfe gGmbH [PDF]

Health Economics and Management Review
This article explores the application of the SCRUM methodology, a popular Agile framework, in social work with children and adolescents exhibiting conduct disorders and antisocial behaviour.
Dimitry Borissov
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Conduct disorder

Nature Reviews Disease Primers, 2019
G. Fairchild, D. Hawes, P. Frick, William E. Copeland, C. Odgers, B. Franke, C. Freitag, Stephane A. De Brito   +7 more
semanticscholar   +2 more sources

Skin Conductance Responses and Neural Activations During Fear Conditioning and Extinction Recall Across Anxiety Disorders [PDF]

, 2017
Marie‐France Marin, Rachel G. Zsido, Huijin Song, Natasha B. Lasko, William D. S. Killgore, Scott L. Rauch, Naomi M. Simon, Mohammed R. Milad   +7 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A follow-up study of academic functioning and social adjustment in children with attention deficit hyperactivity disorder

Indian Journal of Psychological Medicine, 2013
Background : Attention deficit hyperactivity disorder (ADHD) persists in a majority of adolescents. It has been reported that ADHD patients have poor social functioning and risk for developing co-morbid psychiatric illnesses.
Jasmin Garg, Priti Arun
doaj   +1 more source