Results 131 to 140 of about 255,109 (301)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Family Functioning in Attention Deficit Hyperactivity Disorder with or without Oppositional Defiant Disorder/Conduct Disorder Comorbidity

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2013
Purpose: The purpose of the study was to examine family functioning in attention deficit and hyperactivity disorder (ADHD) and ADHD comorbid with oppositional defiant disorder ( ODD) or conduct disorder ( CD).
Sebla Gokce Imren   +4 more
doaj  

The Tendency of Conduct Disorder in Terms of Authoritarian Parenting and Gender

open access: yesAnfusina: Journal of Psychology
Lampung Province has a rather high crime rate, particularly since most of these criminals are still in adolescence. Teenagers who engage in such criminal action are more likely to repeat the act, which might be categorized as a conduct disorder tendency.
Prida Harkina   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Conduct disorder and oppositional defiant disorder [PDF]

open access: yes, 2016
Conduct disorder and oppositional defiant ...
Jessica Green (13354326)   +2 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Risks associated with conduct disorder in girls [PDF]

open access: yes, 2003
Conduct disorder is the second most common psychiatric disorder in adolescent girls. In a secondary analysis of an existing data set from a study of pregnant adolescent girls, recruited from three different sites in a Canadian city (N = 252), possible
Green, Tara
core  

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