Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
What are effective treatments for oppositional defiant behaviors in adolescents? [PDF]
, 2006 Psychological interventions for the family-- such as parenting skills training and behavioral therapy for the child, the parents, or the whole family--reduce conflict behaviors in adolescents with oppositional defiant disorder (ODD) (strength of ...
Kelsberg, Gary, St. Anna, Leilani
core
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Multipotent Mesenchymal Stem Cell Therapy for Vascular Dementia
CellsVascular dementia (VD), characterized by cognitive decline and behavioral disorders, has seen a rapid increase in prevalence in recent years. However, effective treatments for VD remain unavailable.
Eun-Young Kim +7 more
doaj +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Enhancing mentalization by specific interventions within mentalization-based treatment of adolescents with conduct disorder. [PDF]
Front Psychol, 2023 Kasper LA +3 more
europepmc +1 more source
TIGA-CUB-manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5–11 with treatment-resistant conduct disorders and their primary carers: results from a randomised controlled feasibility trial [PDF]
, 2018 Elizabeth Edginton +14 more
openalex +1 more source
Genetic influences on conduct disorder
Neuroscience and Biobehavioral Reviews, 2018 J. Salvatore, D. Dick
semanticscholar +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Examining the clinical correlates of conduct disorder in youth with bipolar disorder. [PDF]
J Affect Disord, 2023 Woodward D +9 more
europepmc +1 more source