Results 91 to 100 of about 11,831,950 (329)

ELGESIO SUTRIKIMŲ TURINČIŲ PAAUGLIŲ EGO FUNKCIJOS IR JŲ RYŠYS SU ĮVEIKOS STRATEGIJOMIS

open access: yesPsichologija, 2007
Straipsnyje nagrinėjamos elgesio sutrikimų turinčių paauglių Ego funkcijos (ryšiai su objektais, impulsų ir afektų kontrolė, gynybinis bei sintetinis integracinis funkcionavimas) ir jų ryšys su įveikos strategijomis.
Vaida Kalpokienė, Gražina Gudaitė
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Prevention of conduct disorders: cognitive behavioural approaches

open access: yes, 2013
Introduction The burden of conduct disorders Conduct disorders are characterised by persistent antisocial behaviour in children and young people and are remarkably common: at the level of diagnosable disorders, even using relatively conservative criteria,
Scott, Stephen, Stephen Scott
core   +1 more source

Conduct disorders in children and adolescents

open access: yes, 1995
Conduct disorder is the most prevalent emotional disorder in children and adolescents and therefore requires special attention from clinicians. Conduct Disorders in Children and Adolescents provides a comprehensive and balanced view of this disorder.
Sholevar, G. P.
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The New Multi-Ministry Response to Conduct Problems: A SWOT analysis

open access: yes, 2008
The Inter-agency Plan for Conduct Disorder/Severe Antisocial Behaviour 2007-2012 (Ministry of Social Development, 2007) is assessed according to the SWOT dimensions of strengths, weaknesses, opportunities and threats.
Stanley, Peter
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Conduct disorders among adolescents in te context of socialization [PDF]

open access: yes, 2008
This thesis is discussing conduct disorders among children and adolescents. The goal of this thesis is to map risk and dangerous factors and their influence in a context of socialization and look into its nature in relation to their acts of behavior.
Kajuková, Věra
core   +1 more source

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