Results 71 to 80 of about 11,831,950 (329)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
-5 Disruptive, Impulse Control, and Conduct Disorders
The assessment of oppositional defiant disorder, conduct disorder, antisocial personality disorder, and intermittent explosive disorder—the Disruptive, Impulse Control and Conduct Disorders—can be affected by biases in clinical judgment, including ...
Jeffrey D. Burke +9 more
core +1 more source
Decades of research has shown that youths with conduct disorder (CD) represent a highly heterogeneous population. Over the past 20 years, most of the research and clinical work have focused on two sub-typing approaches to characterize the heterogeneity within CD: (1) the age of onset distinction introduced in DSM-IV and (2) the presence of callous ...
Clanton, Roberta L. +3 more
+5 more sources
Background The effects of pandemic-related restrictions on people in prisons who tend to have multiple complex health needs are not well understood. Aims We aimed to measure changes in adjudications and self-harm among people in prisons before and ...
Steven M. Gillespie +8 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Do historical changes in parent-child relationships explain increases in youth conduct problems?
The coincidence of historical trends in youth antisocial behavior and change in family demographics has led to speculation of a causal link, possibly mediated by declining quality of parenting and parent-child relationships. No study to date has directly
Collishaw, Stephan +9 more
core +1 more source
Chronological relationship between antisocial personality disorder and alcohol dependence [PDF]
Personality disorders, and particularly antisocial personality disorder (ASPD), frequently co-occur with alcohol dependence. ASPD is considered to be an important cofactor in the pathogenesis and clinical course of alcohol dependence.
Preuss, Ulrich W. +2 more
core +1 more source
Conduct disorder is a serious mental disorder with a heterogeneous etiology that is frequently encountered in child and adolescent psychiatric clinics, although there are social and international differences.
Ahmet Özbay +2 more
doaj +1 more source
The adult outcome of hyperactive boys with attention deficit hyperactivity disorder was evaluated by prospective follow-up and direct psychiatric interviews of 85 probands and 73 comparison subjects at the Child and Adolescent Behavior Center, Long ...
J Gordon Millichap
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

