Results 91 to 100 of about 7,267,381 (385)

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

Anomalous differential conductance of In-Bi2Te3 contact [PDF]

open access: yesarXiv, 2011
The differential conductance of In/Bi2Te3 contact under cryogenic temperature is investigated. Anomalous zero/finite bias differential conductance has been observed. The dependence of the observed anomalous differential conductance on magnetic field and temperature is studied.
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Anatomical and physiological characteristics of two argentine wheat cultivars Características anatômicas e fisiológicas de dois cultivares argentinos de trigo

open access: yesCiência Rural, 2003
Two Argentine field grown wheat cultivars (Triticum aestivum L.), Buck Cencerro (BC) with traditional germoplasm, and Buck Pucará (BP) with Mexican germoplasm, have been investigated in order to compare anatomical and physiological characteristics of the
Raúl Roberto Filgueira   +3 more
doaj   +1 more source

First-Principles Study on Electron-Conduction Properties of C$_{60}$ Chains [PDF]

open access: yes, 2006
The electron-conduction properties of fullerene chains are examined by first-principles calculations based on the density functional theory. The conductivity of the C$_{60}$ dimer is low owing to the constraint of the junction of the molecules on electron conduction, whereas the C$_{60}$ monomer exhibits a conductance of $\sim$ 1 G$_0$.
arxiv   +1 more source

Thermal conductance of metal–diamond interfaces at high pressure

open access: yesNature Communications, 2015
The thermal conductance of interfaces between metals and diamond, which has a comparatively high Debye temperature, is often greater than can be accounted for by two-phonon processes.
Gregory T. Hohensee   +2 more
semanticscholar   +1 more source

On the conductivity of snow [PDF]

open access: yesThe London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, 1891
n ...
openaire   +2 more sources

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

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