Results 101 to 110 of about 1,088,283 (304)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Intrinsic nonlinear conductivity induced by quantum geometry in altermagnets and measurement of the in-plane Néel vector [PDF]

Phys. Rev. B 110, L241405 (2024)
The $z$-component of the N\'{e}el vector is measurable by the anomalous Hall conductivity in altermagnets because time reversal symmetry is broken. On the other hand, it is a nontrivial problem how to measure the in-plane component of the N\'{e}el vector. We study the second-order nonlinear conductivity of a system made of the $d$-wave altermagnet with
arxiv   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Introduction to cardiac electrophysiology and assessment of sinus node and atrio-ventricular conduction

Ibom Medical Journal
Background: Interest in cardiac electrophysiology is increasing in sub-Saharan Africa, but the interpretation of results is poorly understood. Cardiac electrophysiology is the study of electrical activity of the heart by virtue of catheters that are ...
Uwanuruochi K, Ruchit S, Kokane HT
doaj   +1 more source

Unusual Length Dependence of Conductance of Some Oligomers [PDF]

arXiv, 2006
Recent experiment found a quantum length dependence of oligothiophene molecule conductance at low bias [Xu et al., nano Lett. \textbf{5}, 1491 (2005)], the long molecule has large conductance. By means of a first-principles method we obtain both the quantum length dependence of conductance at low bias and the classical length dependence of conductance ...
arxiv  

Conduction at domain walls in insulating Pb(Zr$_{0.2}$Ti$_{0.8}$)O$_3$ thin films

, 2011
Among the recent discoveries of domain wall functionalities, the observation of electrical conduction at ferroelectric domain walls in the multiferroic insulator BiFeO3 has opened exciting new possibilities.
Aguado-Puente, Bilc, Béa, Catalan, Chiu, Daraktchiev, Eliseev, Farokhipoor, Fowler, Gariglio, Guyonnet, Jeong, Jia, Jia, Kubel, Lee, Lubk, Maksymovych, Maksymovych, Maksymovych, Martin, Paruch, Paruch, Paruch, Pintilie, Salje, Seidel, Seidel, Sze, Tsymbal, Zubko   +30 more
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Corrigendum: The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism

Frontiers in Physiology, 2022
Xin Liu, Xin Liu, Xin Liu, Chuan Qu, Chuan Qu, Chuan Qu, Shaobo Shi, Shaobo Shi, Shaobo Shi, Tianxin Ye, Tianxin Ye, Tianxin Ye, Linglin Wang, Linglin Wang, Linglin Wang, Steven Liu, Steven Liu, Steven Liu, Cui Zhang, Cui Zhang, Cui Zhang, Jinjun Liang, Jinjun Liang, Jinjun Liang, Dan Hu, Dan Hu, Dan Hu, Bo Yang, Bo Yang, Bo Yang   +29 more
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source