Results 211 to 220 of about 1,430,098 (378)

Transient Complete Atrioventricular Block During Routine Colonoscopy: A Benign Vagal Reflex Mimicking Conduction System Disease. [PDF]

Cureus
Hernandez Mejia S, Fahed J, Isber R, Isber N.   +3 more
europepmc   +1 more source

Effects of heating strategies and ballistic transport on the transient thermal conduction in 3D FinFETs [PDF]

Chuang Zhang, Z.H. Xin, Qin Lou, Hong Liang   +3 more
openalex   +1 more source

Enhanced single-ion conduction and free-standing properties of solid polymer electrolyte by incorporating a polyelectrolyte

, 2021
Tewuhibo S Mengistie, Jang Myoun Ko, Jung Yong Kim   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The Effectiveness of Cryoflow Cooling on Forearm Skin Temperature and Nerve Conduction Velocity in Normal Subjects: A Case-Control Study. [PDF]

NeuroSci
Alayat MS, Battecha KH, Jabr YS, Zagzoog F, Hasaballah B, Alsulami FFS, Refaei MA, Almehmadi OS.   +7 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Conduction Block Detection in Dysimmune Neuropathy: Hypothetical Pathophysiological 'Truth' Versus Clinical Pragmatism. [PDF]

Eur J Neurol
Rajabally YA, Al-Areed A.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Incidence and In-Hospital Outcomes of Bradycardia or Atrioventricular Conduction Disorder in Patients With Type 2 Myocardial Infarction: A Nationwide Inpatient Analysis. [PDF]

J Arrhythm
Puchongmart C, Lorlowhakarn K, Soliman D, Danpanichkul P, Chaisrimaneepan N, Leelaviwat N, Swaminath D, Thiravetyan B.   +7 more
europepmc   +1 more source

Conduction disturbances caused by high current density electric fields. [PDF]

, 1990
Seitaro Yabe, W.M. Smith, James P. Daubert, Patrick D. Wolf, Dennis L. Rollins, R.E. Ideker   +5 more
openalex   +1 more source