Results 111 to 120 of about 2,933 (260)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Flexo-Pyroelectric Effect. [PDF]

open access: yesResearch (Wash D C)
Gao W, Liu S, Qin Y.
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Analysis of the thermal plumes in turbulent Rayleigh-Bénard convection based on well-resolved numerical simulations

open access: yes, 2008
For the study presented DNS and high-resolved LES of turbulent Rayleigh-Bénard convection were conducted with fluid of Pr=0.7 in a long rectangular cell of aspect ratio unity in the cross-section and periodic boundaries in a horizontal longitudinal ...
Kaczorowski, Matthias, Wagner, Claus
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Polyacid Solutions as an Analogue of a Neural Network. [PDF]

open access: yesPolymers (Basel)
Kabdushev S   +5 more
europepmc   +1 more source

Superconductivity and Ferroelectricity

open access: yes, 2016
International audienceSuperconductivity and ferroelectricity appear at first sight as mutually exclusive phenomena. Indeed, the local electric fields generated by the dipoles at the heart of ferroelectricity should be screened by conduction electrons ...
Kiat, Jean-Michel   +2 more
core  

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