Results 41 to 50 of about 52,303 (319)

Assessment of condylar and glenoid fossa dimension in various sagittal skeletal malocclusions

Journal of Orthodontic Science
INTRODUCTION: Jaw mobility and oral function depend on the temporomandibular joint (TMJ), with the dimensions of the mandibular condyle and glenoid fossa being important for understanding dental and orthodontic conditions. Additionally, advanced imaging,
Ashish Ravi Kallur, Remmiya Mary Varghese   +1 more
doaj   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

Advanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng, Jing‐Rong Cheng, Yu Qin, Jie Lei, Chen‐Chen Gao, Hong‐Ying Fu, Li‐Ping Wu, Thanh D. Nguyen, Xu‐Liang Deng, Kai‐Yuan Fu, Yang Liu   +10 more
wiley   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

Advanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen, Jiaying Li, Jinjin Ma, Xiaonan Yuan, Yao Xiao, Yang Zhang, Yuan Chen, Hao Jiang, Hui He, Jie Hu, Qianglong Chen, Jinniu Zhang, Bin Li, Yun Zhou, Fengxuan Han, Yong Wang   +15 more
wiley   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Endoscope-Assisted or Skin-Approach Osteosynthesis of Mandibular Condylar Fracture—A Comparison

Journal of Functional Biomaterials
Open reduction and internal fixation (ORIF) for mandibular condyle fractures remains a controversial and challenging issue, with the exception of basal and low-neck fractures.
Paulina Agier, Dominik Szczeciński, Marcin Kozakiewicz   +2 more
doaj   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Cambios morfológicos de la articulación temporomandibular en relación con el estado dental: un estudio con material cadavérico

Revista Facultad de Odontología Universidad de Antioquia, 1999
Objective: The purposes in this study were determine the size of structure of temporomandibular joint, the morphology of mandibular condile, the presence of osteoarthritis (OA) and determine the association between dental state and condile remodelation ...
José Domingo García-L. , Luis Ernesto Ballesteros-A.   +1 more
doaj  

Plate Breakage After Mandibular Condylar Fracture Osteosynthesis

Journal of Functional Biomaterials
Despite the significant ongoing development of fixation materials, plate breakages still occur after osteosynthesis of the mandibular condyles. The aim of this study is to demonstrate the complications caused by fixation material breakages in the hope of
Marcin Kozakiewicz, Paulina Agier, Paulina Pruszyńska   +2 more
doaj   +1 more source

Imaging of osteochondroma of the temporomandibular joint – Report of two cases

Journal of Oral and Maxillofacial Radiology, 2020
Osteochondroma of mandibular condyle is an uncommon entity. In the temporomandibular region, they usually present as restriction in mouth opening and pain in the joint. They can grow to a large size to impinge upon the cranial fossa.
Ruchi Gupta, Sailesh Kumar Mukul, Abhishek Singh, Subhash Kumar   +3 more
doaj   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source