Results 61 to 70 of about 94,597 (350)

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

Effectiveness of Open Rigid Internal Fixation of Condylar Fracture Resulting in Temporomandibular Joint Function Recovery

Dentistry Journal
Background: Maxillofacial trauma can impair crucial functions of the stomatognathic system. Mandibular condyle fractures, in particular, often lead to temporomandibular joint (TMJ) dysfunction.
Paulina Agier, Szymon Tyszkiewicz, Marcin Kozakiewicz   +2 more
doaj   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

Advanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao, Wei Li, Zhencan Lin, Zengfa Deng, Ming Li, Zongrui Jiang, Changzhao Li, Dianbo Long, Yan Kang   +8 more
wiley   +1 more source

Cambios morfológicos de la articulación temporomandibular en relación con el estado dental: un estudio con material cadavérico

Revista Facultad de Odontología Universidad de Antioquia, 1999
Objective: The purposes in this study were determine the size of structure of temporomandibular joint, the morphology of mandibular condile, the presence of osteoarthritis (OA) and determine the association between dental state and condile remodelation ...
José Domingo García-L. , Luis Ernesto Ballesteros-A.   +1 more
doaj  

Assessment of condylar and glenoid fossa dimension in various sagittal skeletal malocclusions

Journal of Orthodontic Science
INTRODUCTION: Jaw mobility and oral function depend on the temporomandibular joint (TMJ), with the dimensions of the mandibular condyle and glenoid fossa being important for understanding dental and orthodontic conditions. Additionally, advanced imaging,
Ashish Ravi Kallur, Remmiya Mary Varghese   +1 more
doaj   +1 more source

Open reduction internal fixation of lateral humeral condyle fractures in children. A series of 105 fractures from a single institution

Strategies in Trauma and Limb Reconstruction, 2014
Lateral humeral condyle fractures account for 17 % of the distal humeral condyle fractures. Displaced and/or rotated fractures require appropriate reduction and stabilisation.
A. Leonidou, K. Chettiar, S. Graham, P. Akhbari, Konstantinos Antonis, E. Tsiridis, O. Leonidou   +6 more
semanticscholar   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Imaging of osteochondroma of the temporomandibular joint – Report of two cases

Journal of Oral and Maxillofacial Radiology, 2020
Osteochondroma of mandibular condyle is an uncommon entity. In the temporomandibular region, they usually present as restriction in mouth opening and pain in the joint. They can grow to a large size to impinge upon the cranial fossa.
Ruchi Gupta, Sailesh Kumar Mukul, Abhishek Singh, Subhash Kumar   +3 more
doaj   +1 more source

Osteochondroma of Mandibular Condyle [PDF]

, 1970
Osteochondroma is one of the most common benign bone tumor of axial skeleton. In oral and maxillofacial region, osteochondroma is rare. This tumor most often involves mandibularcoronoid process however the osteochondroma of mandibular  ...
Chaurasia, Akhilanand
core  

Bifid mandibular condyle: A rare disorder

, 2006
Bifid mandibular condyle is a rare disorder and little is known about the etiology and pathogenesis. We reported a patient with left bifid mandibular condyle with a history of trauma.
Mavili, M. Emin, Tuncbilek, Goekhan, Cavdar, Guenay   +2 more
core   +1 more source