Results 91 to 100 of about 56,714 (261)
Advanced Functional Materials, EarlyView.Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro +25 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
An index formula for the intersection Euler characteristic of an infinite cone
Comptes Rendus. Mathématique, 2016 The aim of this note is to establish an index formula for the intersection Euler characteristic of a cone. The main actor of these notes is the model Witten Laplacian on the infinite cone. First, we study its spectral properties and establish a McKean–Singer-type formula.
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Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez +8 more
wiley +1 more source
Revista de la Facultad de Ciencias Agrarias, 2019 The objective of this work was to evaluate the effect of repeated traffic with a light-weight tractor on the physical/mechanical properties of an Aridisol soil from eastern Almería (Spain).
Guido Fernando Botta +7 more
doaj
The regularity index and the depth of the tangent cone of curve singularities
Japanese journal of mathematics. New series, 1996 The author studies numerical invariants of ``curves'', i.e. one-dimensional Cohen-Macaulay rings \((A,{\mathfrak m})\), and investigates their relation to the Cohen-Macaulay property of the tangent cone of \(R\), i.e. the associated graded ring \(\text{gr}_{\mathfrak m}(A)\).
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.A biocompatible sodium alginate‐based hydrogel is developed as a next‐generation submucosal lifting agent intended for EMR and ESD. The optimized formulation exhibits a composition devoid of endotoxins, high viscosity, demonstrates reliable injectability, and ensures prolonged mucosal elevation.
Iram Maqsood +9 more
wiley +1 more source
Science ProgressCompared with plane cutterhead, the cone-shape cutterhead has better rock-breaking performance with a free surface during the rock-breaking process. Tunneling parameters of cone-shaped cutterhead have great influence on the rock-breaking efficiency and ...
Laikuang Lin +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.(A) Isolation and purification of LDNVs. (B) Establishment of the ALI model and LDNVs delivery. (C) Therapeutic mechanisms of LDNVs in treating ALI. This scheme figure was drawn by Figdraw, ID: IUIIO21222. ABSTRACT Acute lung injury (ALI) is a lethal respiratory disease.
Xi Lin +10 more
wiley +1 more source