Results 21 to 30 of about 88,835 (298)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Simulation of penetration problems in geomechanics [PDF]

open access: yes, 2017
The simulation of penetration problems in geomaterials is a challenging problem as it involves large deformations and displacements as well as strong non-linearities affecting material behaviour, geometry and contact surfaces. The paper presents examples
Arroyo, Marcos   +4 more
core   +3 more sources

Cone Penetration Testing in Polar Snow [PDF]

open access: yesOTC Arctic Technology Conference, 2011
Abstract Rate-controlled Cone Penetration Testing (CPT) using unique portable equipment was recently conducted in Antarctica. This testing was undertaken in an attempt to investigate the strength and thence bearing capacity of polar snow via insitu means.
A.B. McCallum, A. Barwise, R. Santos
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Microstructural study of the deformation zones around a penetrating coned tip in silty soil [PDF]

open access: yes, 2015
The change in soil microstructure around the penetrating probe during a cone penetration test is investigated. Backscattered electron images of polished thin sections prepared from frozen samples at the end of penetration are used.
Fonseca, J.   +3 more
core  

Optimizing Post Friction Stir Welding Heat Treatment in Dissimilar Friction Stir Welded 6061/AlSi10MgMn Joints for Electrical Vehicle Battery Housing

open access: yesAdvanced Engineering Materials, EarlyView.
Microstructural evolution and hardness optimization along the cross‐section of friction stir welded AA6061/AlSi10MgMn joints, for electric vehicle battery housings, were investigated. Postweld aging between 170°C and 220°C enhances hardness uniformity within the nugget zone.
Emanuele Ghio, Emanuela Cerri
wiley   +1 more source

Advancing Research on Biomaterials and Biological Materials with Scanning Electron Microscopy under Environmental and Low Vacuum Conditions

open access: yesAdvanced Engineering Materials, EarlyView.
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel   +6 more
wiley   +1 more source

Can Ti‐Based MXenes Serve as Solid Lubricants for Brake Applications? A Tribological Study

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores the first implementation of Ti‐based MXenes materials in brake pad friction composite material. The resulting composite material exhibits a 48% reduction in the wear rate; alongside significant improvements are observed for thermal and mechanical properties.
Eslam Mahmoud   +7 more
wiley   +1 more source

Integrated geotechnical and geophysical investigation of a proposed construction site at Mowe, Southwestern Nigeria [PDF]

open access: yes, 2018
The subsurface of a proposed site for building development in Mowe, Nigeria, using Standard Penetration Test (SPT), Cone Penetrometer Test (CPT) and Horizontal Electrical Profiling (HEP), was investigated with the aim of evaluating the suitability of the
Nduka, Adaobi C.   +2 more
core  

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