Results 31 to 40 of about 152,539 (295)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Historia, vida y contradicciones en las Trece Colonias
Alejandría, 2023 In this brief article I expose the historical conditions prior to the colonization of North America, the colonization itself together with its previous historical context and the social conditions of these settlers.
José Antonio Martínez Amador
doaj
Ler História, 2008 This article aims at understanding the formation of the concept of federalism and of provincial interest in the Brazilian political debate of the XIXth century.
Ivo Coser
doaj +1 more source
Elimination of All Forms of Forced or Compulsory Labor [PDF]
, 2001 A compilation of reports submitted by various countries to the ILO by the year 2000, describing labor conditions and relevant laws, specifically relating to forced or compulsory ...
International Labour Office +1 more
core +1 more source
In search of the authentic nation: landscape and national identity in Canada and Switzerland [PDF]
, 1998 While the study of nationalism and national identity has flourished in the last decade, little attention has been devoted to the conditions under which natural environments acquire significance in definitions of nationhood.
Alter Peter +97 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
From Discord to Autonomy: The Idea of Unity between Georgia and the North Caucasus, 1917–1920 [PDF]
Plural: History, Culture, SocietyThis study explores the evolution of relations between Georgia and the North Caucasian Mountain Republic from 1917 to 1920 in the context of revolution, independence, and regional crises.
Giorgi Batsikadze +2 more
doaj +1 more source
Representativeness of the European Social Partner Organizations: Tanning and Leather Industry [PDF]
, 2017 This study provides information designed to encourage sectoral social dialogue in the tanning and leather sector. The aim of Eurofound’s series of studies on representativeness is to identify the relevant national and supranational social partner ...
Adam, Georg, Allinger, Bernadette
core +1 more source
Underwater acoustic slant range measurements related to weather and sea state [PDF]
, 2018 Underwater range measurements are key factor in underwater acoustic positioning, used in Long Base-Line (LBL) or Ultra Short Base-Line (USBL) computing techniques. These measurements are commonly carried out through acoustic communications between modems
Aguzzi, Jacopo +5 more
core +1 more source