Results 111 to 120 of about 9,670,350 (261)
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Proceedings : 68th Annual Pacific Northwest Insect Management Conference [PDF]
Proceedings of the 68th Annual Pacific Northwest Insect Management Conference, held January 12 & 13, 2009 at the Hilton Hotel, Portland ...
Pacific Northwest Insect Management Conference
core
Building Capacity and Strengthening Collaboration: A PBRN Conference Update. [PDF]
Haddad L, Gross N.
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Proceedings : 69th Annual Pacific Northwest Insect Management Conference [PDF]
Proceedings of the 69th Annual Pacific Northwest Insect Management Conference, held January 11-12, 2010 at the Hilton Hotel in Portland ...
Pacific Northwest Insect Management Conference
core
A learner-led conference to enhance interdisciplinary social accountability education in healthcare: participant perspectives on engagement and educational experience. [PDF]
Chopra M +4 more
europepmc +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Research reports : 48th annual Pacific Northwest Vegetable Insect Conference
Proceedings of the 48th Pacific Northwest Vegetable Insect Conference, held January 9-10, 1989 at the Imperial Hotel in Portland ...
Pacific Northwest Vegetable Insect Conference
core

