Results 61 to 70 of about 9,670,350 (261)

International Conference on Continuous Media with Microstructure

open access: yesEngineering Transactions, 2015
The 2nd conference CMwM is organized in memory of Professor Krzysztof Wilmański who regrettably passed away on 26 August 2012. The 1st conference CMwM took place in Zielona Gόra in 2010 to celebrate the 70th birthday of Professor Krzysztof Wilmański (b ...
INTERNATIONAL CONFERENCE
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Ohio Judicial Conference ... biennial report; Biennial report

open access: yes
Biennial; "Presented at the Ohio Judicial Conference Annual Meeting ..."; Description based on: 2008; title from PDF cover (viewed on Jan.
Ohio Judicial Conference.
core  

Research reports: 76th Annual Pacific Northwest Insect Management Conference [PDF]

open access: yes
Proceedings of the 76th Annual Pacific Northwest Insect Management Conference, held January 9-10, 2017 at Hilton Hotel, Portland ...
Pacific Northwest Insect Management Conference
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Research reports : 81st Annual Pacific Northwest Insect Management Conference [PDF]

open access: yes
Proceedings of the 81st Annual Pacific Northwest Insect Management Conference, held virtually January 10-11, 2022.
Pacific Northwest Insect Management Conference
core  

Our Shared Responsibility to End Plastic Pollution, Protect Human Health, and Advance Social Justice for All

open access: yesJournal of Moral Theology
Continuing unchecked increases in plastic production are unethical and immoral. Moreover, continuing increases in plastic production and use are responsible for damages that threaten all forms of life on earth. Resolute international actions, including a
Conference Participants
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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