Results 31 to 40 of about 11,556,529 (242)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Special Issue: 2018 Research Data Access and Preservation Summit
Journal of eScience Librarianship, 2018 The Journal of eScience Librarianship partners with the Research Data Access & Preservation (RDAP) Association to publish selected conference proceedings.
Tina Griffin +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
International Conference on Industry, Engineering, and Management Systems 2024
Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, November 2024. 2024 IEMS Officers: Gamal Weheba (Conference Chair); Hesham Mahgoub (Program Chair); Dalia Mahgoub (Technical Director); Ed Sawan ...
International Conference on Industry, Engineering, and Management Systems
core +1 more source
SEE 2007 Conference Proceedings [PDF]
, 2007 In 2007, the conference "Software & Systems Engineering Essentials" was organized by 4Soft, a software and consulting company from Munich, and the Clausthal University of Technology.
Rausch, Andreas +2 more
core
Issues in Science and Technology Librarianship, 2014 Conference proceedings represent a large part of the literature in computer science. Two Conference Proceedings Citation Index databases were merged with Web of Science in 200: but very few studies have been conducted to evaluate the effect of that ...
Li Zhang
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Slavica Revalensia, 2016 In his contribution to the second volume of Slavica Revalensia, Sergei Shindin reviews the proceedings of the Warsaw Mandel’shtam conference (September 18—22, 2011) published in 2013 by the Russian State University for the Humanities.
Sergei Shindin
doaj +1 more source