Results 51 to 60 of about 13,845,352 (220)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Conference Proceedings 5th Blockchain International Scientific Conference ICS2023

open access: yes, 2023
Conference Proceedings 5th Blockchain International Scientific Conference ICS2023 held in Manchester, UK, on 18 March ...
The British Blockchain Association
core  

Proceedings of the 1966 invitational conference on testing problems

open access: yes, 1966
La couv.
Educational Testing Service Invitational Conference on Testing Problems. Proceedings (1966 : New York)
core   +1 more source

Conference Proceedings, 3rd Blockchain International Scientific Conference, ISC2021

open access: yesThe Journal of The British Blockchain Association, 2021
Conference Proceedings, 3rd Blockchain International Scientific Conference ...
Naseem Naqvi
doaj  

Services conference as an answer to challenges of administrative procedure

open access: yesBratislava Law Review, 2018
The paper presents the services conference as one of the forms of conducting administrative proceedings. The starting point is to present an institution shaped in the Italian procedural law in the light of its administrative system and its evolutionary ...
Robert Siuciński
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

open access: yesFEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li   +7 more
wiley   +1 more source

Premable to, Fifth International Conference on Quantitative Ethnography: CONFERENCE PROCEEDINGS SUPPLEMENT

open access: yes, 2023
This volume represents the supplementary proceedings of the Fifth International Conference on Quantitative Ethnography (ICQE23). This year’s event represents the first ICQE in Australasia, following 2022’s inaugural European event (Copenhagen, ICQE22 ...
Arastoopour Irgens, G, Knight, S
core  

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

open access: yesFEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

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