Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
“Reconfiguring Human and Non-Human: Texts, Images and Beyond”
Fafnir, 2015 The relevance of the seminar Reconfiguring Human and Non-Human: Texts, Images and Beyond, which was held in Jyväskylä from October 29th to 30th, was demonstrated by the influx of participants.
Jani Ylönen
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
IZVJEŠTAJI // CONFERENCE REPORTS: AKTIVNOSTI CENTRA ZA ISTRAŽIVANJE MODERNE I SAVREMENE HISTORIJE TUZLA U 2019. GODINIACTIVITIES OF CENTER FOR RESEARCH OF MODERN AND CONTEMPORARY HISTORY TUZLA IN 2019. [PDF]
Historijski pogledi, 2020 IZVJEŠTAJI // CONFERENCE REPORTS: AKTIVNOSTI CENTRA ZA ISTRAŽIVANJE MODERNE I SAVREMENE HISTORIJE TUZLA U 2019. GODINIACTIVITIES OF CENTER FOR RESEARCH OF MODERN AND CONTEMPORARY HISTORY TUZLA IN 2019.
Jasmin Jajčević
doaj
Nordic Jews in the twentieth and twenty-first centuries
Nordisk Judaistik, 2020 Conference report on the online workshop ‘Nordic Jews in the 20th and 21st centuries: Multiple Identifications in Everyday Life’, organized by Professor Lena Roos, 15–16 October 2020.
Dóra Pataricza
doaj +1 more source
Sprawozdanie z XXV Światowego Kongresu Politologicznego, Brisbane, 21–25 lipca 2018 r. [PDF]
Nowa Polityka Wschodnia, 2018 Report from the 25th World Congress of Political Science, Brisbane, July 21–25 ...
Arkadiusz Żukowski
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Volles Haus beim Niedersächsischen Bibliothekstag 2018
o-bib. Das offene Bibliotheksjournal, 2019 Tagungsbericht
Ellen van der Loos, Corinna Roeder
doaj +1 more source
Sprawozdanie z V Ogólnopolskiej Konferencji Naukowej „Teoretyczne i empiryczne aspekty badań nad bezpieczeństwem międzynarodowym”, Toruń, 28 czerwca 2019 roku [PDF]
Nowa Polityka Wschodnia, 2019 Report from the V Conference “Theoretical and Empirical Aspects of International Security”, Toruń, June 28 ...
Kamila Sara Kowalska
doaj +1 more source