Results 61 to 70 of about 280,632 (260)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Conference Report: The Legacies of Ursula K. Le Guin

Fafnir, 2019
When Ursula K. Le Guin passed away last January, her absence left a hole in the hearts of many in the speculative-fiction community, as much for loss of her personal grace and wit as for her outsized contributions to the field. Understandably, many felt
Dennis Wilson Wise
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Fantastic Conference Days in Sunny Florida

Fafnir, 2014
Report from the 35th International Conference on the Fantastic in the Arts.
Päivi Väätänen
doaj  

Proceedings of the ‘18th International Conference of Ethiopian Studies: Movements in Ethiopia/Ethiopia in Movement’ Dire Dawa, Ethiopia, October 29–November 2, 2012. Panel on Manuscript Studies

Aethiopica, 2016
Conference ...
Alessandro Bausi, Denis Nosnitsin
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The Dark Side of the Sheep, and Other Animals

Fafnir, 2015
Report from the Thirty-Sixth International Conference on the Fantastic in the Arts, March 18-22, 2015.
Kaisa Kortekallio
doaj  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The Promises of Monsters

Fafnir, 2016
One cold April, in a clean, quiet town in Norway, a monster was born. Though it sounds like the beginning of a fairy tale or a horror novel, it is actually the story of an academic conference: “Promises of Monsters”, at the University of Stavanger.
Megen de Bruin-Molé
doaj  

IZVJEŠTAJ/CONFERENCE REPORT Izvještaj sa okruglog stola “HISTORIJSKI ZNAČAJ PRIJEMA REPUBLIKE BOSNE I I HERCEGOVINE U ČLANSTVO ORGANIZACIJE UJEDINJENIH NACIJA – 26 godina poslije”, Tuzla, 15. decembar 2018. godine [PDF]

Historijski pogledi, 2018
IZVJEŠTAJ/CONFERENCE REPORT Izvještaj sa okruglog stola “HISTORIJSKI ZNAČAJ PRIJEMA REPUBLIKE BOSNE I I HERCEGOVINE U ČLANSTVO ORGANIZACIJE UJEDINJENIH NACIJA – 26 godina poslije”, Tuzla, 15.
Adnan Tinjić
doaj