Results 61 to 70 of about 17,720,586 (299)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Zeitschrift für WortbildungAs reflected in its title, this workshop, which took place from the eighth to the twelfth of April 2024 at Monte Verità, Ascona, Switzerland, focused on constructional perspectives in their application to morphology (Hoffmann & Trousdale 2013).
Regina Ruf, Michael Redmond
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
A United Effort on an Autonomous Island
Fafnir, 2016 Year 2015 saw a Nordic alliance on the Convention front. Instead of hosting their own events on their respective mainlands, Swedish and Finnish fandoms joined forces to hold a con together. They chose the most neutral area possible, Åland, an autonomous
Jani Ylönen
doaj
Feasibility Study for Hubert H. Humphrey Conference Center: Final Report
, 1980 Conference Center Study Committee. (1980). Feasibility Study for Hubert H. Humphrey Conference Center: Final Report.
Conference Center Study Committee
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Conference Report: The Legacies of Ursula K. Le Guin
Fafnir, 2019 When Ursula K. Le Guin passed away last January, her absence left a hole in the hearts of many in the speculative-fiction community, as much for loss of her personal grace and wit as for her outsized contributions to the field. Understandably, many felt
Dennis Wilson Wise
doaj
Report of the Overseas Shipping Conference.
, 1929 Cover title.; (Presented by command: Ordered to be printed, 5th September, 1929).; Covened by the Right Honorable S. M. Bruce, Prime Minister of the Commonwealth of Australia.; "The conference met in Sydney from Thursday, 4th April, till Saturday, 6th ...
Overseas Shipping Conference (1929)
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