Results 61 to 70 of about 1,958,177 (316)

Behaviour change interventions to influence antimicrobial prescribing: a cross-sectional analysis of reports from UK state-of-the-art scientific conferences [PDF]

open access: yes, 2017
Background To improve the quality of antimicrobial stewardship (AMS) interventions the application of behavioural sciences supported by multidisciplinary collaboration has been recommended.
Charani, E   +6 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Business tourism under apartheid: The historical development of South Africa’s conference industry

open access: yesUrbani Izziv, 2019
Conference tourism as part of MICE tourism has attracted a growing international literature. It is argued existing scholarship is overwhelmingly ‘present-minded’ and that historical issues relating to the conference industry often are overlooked.
Christian M. ROGERSON
doaj   +1 more source

Matariki, commodity culture, and multiple identities [PDF]

open access: yes, 2011
The event known as Matariki, the rising of the Pleiades in winter, which Māori take as the mark of the beginning of a new year, was not a strong feature of the wider public sphere for most of the 20th century.
Hardy, Ann
core   +1 more source

Design study of a thermocouple power sensor as a monolithic fin-line [PDF]

open access: yes, 2011
Making traceable power measurements above 110 GHz using current measurement technologies is challenging. We investigate a design of power sensor consisting of a thermocouple-based integrated circuit (IC) mounted as a finline component in WR-6 waveguide ...
Jones, Mark Hedley, Scott, Jonathan B.
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Online legacy preservation for humanities researchers [PDF]

open access: yes, 2014
As researchers retire or pass away, the online record of their work and their research careers begins to fragment and fade away. We begin with case studies of four New Zealand Humanities researchers, nearing or at the ends of their active careers.
Cunningham, Sally Jo, Nichols, David M.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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