Results 101 to 110 of about 7,064,060 (304)
Confidence with confidence intervals [PDF]
M O, Columb, H E, Thomson
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Competent but Not Confident? [PDF]
Newly qualified GPs are not as well prepared as they used to be. They are ‘competent but not confident’. ‘General practice is different these days’, ‘it is more complicated now’. These were some of the arguments trotted out by some senior members of the College at the 2010 annual RCGP conference in Harrogate, who support the extension of GP training ...
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In this paper, we propose "Confident AI" as a means to designing Artificial Intelligence (AI) and Machine Learning (ML) systems with both algorithm and user confidence in model predictions and reported results. The 4 basic tenets of Confident AI are Repeatability, Believability, Sufficiency, and Adaptability.
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Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Shrinkage Confidence Procedures
The possibility of improving on the usual multivariate normal confidence was first discussed in Stein (1962). Using the ideas of shrinkage, through Bayesian and empirical Bayesian arguments, domination results, both analytic and numerical, have been ...
Casella, George, Hwang, J. T. Gene
core +1 more source
Discounting and Confidence [PDF]
The paper analyzes the discount rate under uncertainty. The analy- sis complements the probabilistic characterization of uncertainty by a measure of confidence. Special cases of the model comprise discounting under smooth am- biguity aversion as well as discounting under a disentanglement of risk aversion from aversion to intertemporal substitution ...
openaire +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Military Regimes In The Sahel As Recruitment Sergeants For Rebel Governance
The recent cases of the de-democratisation of Sahelian states, such as Mali and Burkina Faso, driven by the emergence of military regimes, have been presented as responses to severe security crises occasioned by the activities of transnational violent ...
Samuel Edet +2 more
doaj +1 more source
Confidence bands in nonparametric time series regression
We consider nonparametric estimation of mean regression and conditional variance (or volatility) functions in nonlinear stochastic regression models.
Wu, Wei Biao, Zhao, Zhibiao
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