A Validated Model to Predict Severe Weight Loss in Amyotrophic Lateral Sclerosis
ABSTRACT Severe weight loss in amyotrophic lateral sclerosis (ALS) is common, multifactorial, and associated with shortened survival. Using longitudinal weight data from over 6000 patients with ALS across three cohorts, we built an accelerated failure time model to predict the risk of future severe (≥ 10%) weight loss using five single‐timepoint ...
David G. Lester+4 more
wiley +1 more source
Confidence interval estimation of the common mean of several gamma populations. [PDF]
Yan L.
europepmc +1 more source
Statistics with confidence - confidence intervals and statistical guidelines [PDF]
D. L. Wingate
openalex +1 more source
Redefining the Confidence Interval
The confidence interval, its close cousin the p-value, and other statistical summaries of data are widely used in science, including the occupational and environmental health sciences, but they are almost as widely misused. My purpose here is to review some basic matters that should be covered in every introductory statistics course, but are generally ...
openaire +3 more sources
Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji+9 more
wiley +1 more source
Statistics in Medicine: Calculating confidence intervals for survival time analyses [PDF]
David Machin, Martin J. Gardner
openalex +1 more source
Improved confidence interval for average annual percent change in trend analysis
Hyune-Ju Kim+6 more
semanticscholar +1 more source
ABSTRACT Objective To evaluate the long‐term impact of early intensive treatment (EIT) versus escalation (ESC) strategies using high‐efficacy disease‐modifying therapies (HE‐DMTs) on disability progression in relapsing multiple sclerosis (RMS). Methods This observational study included 4878 RMS patients from the Italian Multiple Sclerosis Register ...
Pietro Iaffaldano+47 more
wiley +1 more source
Application of isotonic regression in estimating EDg and its 95% confidence interval by bootstrap method for a biased coin up-and-down sequential dose-finding design. [PDF]
Hemraj C+3 more
europepmc +1 more source
Confidence intervals and standard errors for ratios of normal variables [PDF]
William P. Dunlap, N. Clayton Silver
openalex +1 more source