Results 51 to 60 of about 3,781,470 (370)
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
Confidence intervals: Concepts, fallacies, criticisms, solutions and beyond [PDF]
For a long time, confidence interval theory is the basis of statistics, and confidence interval has been regarded as an important content of statistical analysis.
WenJun Zhang
doaj
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang+10 more
wiley +1 more source
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang+3 more
wiley +1 more source
Evaluating COVID-19 in Portugal: Bootstrap confidence interval
In this paper, we consider a compartmental model to fit the real data of confirmed active cases with COVID-19 in Portugal, from March 2, 2020 until September 10, 2021 in the Primary Care Cluster in Aveiro region, ACES BV, reported to the Public Health ...
Sofia Tedim+5 more
doaj +1 more source
An SPSS Macro to Compute Confidence Intervals for Pearsons Correlation [PDF]
In many disciplines, including psychology, medical research, epidemiology and public health, authors are required, or at least encouraged to report confidence intervals (CIs) along with effect size estimates.
Bruce Weaver, Ray Koopman
doaj
Fletcher-Turek Model Averaged Profile Likelihood Confidence Intervals [PDF]
We evaluate the model averaged profile likelihood confidence intervals proposed by Fletcher and Turek (2011) in a simple situation in which there are two linear regression models over which we average. We obtain exact expressions for the coverage and the scaled expected length of the intervals and use these to compute these quantities in particular ...
arxiv +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
wiley +1 more source
Becoming confident about confidence intervals [PDF]
A clear understanding of variability is at the heart of many of the studies published in The Bone & Joint Journal . The terms variability, dispersion, spread, distribution and variance, amongst others, are used to refer to the range of values within a dataset.
Perry, DC+5 more
openaire +3 more sources
A common situation in biology is where we have count data and wish to explore whether there is an association between two categorical variables, each with two levels (a 2 × 2 contingency table).
G. Ruxton, M. Neuhäuser
semanticscholar +1 more source