Results 61 to 70 of about 3,781,470 (370)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

How to obtain the P value from a confidence interval

British medical journal, 2011
We have shown in a previous Statistics Note 1 how we can calculate a confidence interval (CI) from a P value. Some published articles report confidence intervals, but do not give corresponding P values.
D. Altman, J. Bland
semanticscholar   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Confidence Interval Estimation of Proportion Near Zero or One: A Modeling Secondary Study

مجله اپیدمیولوژی ایران, 2017
Background and Objectives: When computing a confidence interval for a binomial proportion p, one must choose an exact interval that has a coverage probability of at least 1-α for all values of p.
S Hamzeh, AR Soltanian, J Faradmal
doaj  

Confidence intervals for the difference and the ratio of Lognormal means with bounded parameters [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2015
In this paper, confidence intervals for the difference between lognormal means and the ratio of lognormal means with restricted parameter spaces are proposed.
Sa-aat Niwitpong
doaj  

The P value and statistical significance: Misunderstandings, explanations, challenges, and alternatives

Indian Journal of Psychological Medicine, 2019
The calculation of a P value in research and especially the use of a threshold to declare the statistical significance of the P value have both been challenged in recent years.
Chittaranjan Andrade
doaj   +1 more source

Empirical methods for the validation of time-to-event mathematical models taking into account uncertainty and variability: application to EGFR + lung adenocarcinoma

BMC Bioinformatics, 2023
Background Over the past several decades, metrics have been defined to assess the quality of various types of models and to compare their performance depending on their capacity to explain the variance found in real-life data.
Evgueni Jacob, Angélique Perrillat-Mercerot, Jean-Louis Palgen, Adèle L’Hostis, Nicoletta Ceres, Jean-Pierre Boissel, Jim Bosley, Claudio Monteiro, Riad Kahoul   +8 more
doaj   +1 more source

How to obtain the confidence interval from a P value

British medical journal, 2011
Confidence intervals (CIs) are widely used in reporting statistical analyses of research data, and are usually considered to be more informative than P values from significance tests.1 2 Some published articles, however, report estimated effects and P ...
D. Altman, J. Bland
semanticscholar   +1 more source

A self‐normalized approach to confidence interval construction in time series [PDF]

, 2010
Summary.  We propose a new method to construct confidence intervals for quantities that are associated with a stationary time series, which avoids direct estimation of the asymptotic variances.
Xiaofeng Shao
semanticscholar   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source