Results 71 to 80 of about 3,050,636 (322)
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Comparisons of multivariate GR&R methods using bootstrap confidence interval
Acta Scientiarum: Technology, 2016 This paper aimed to compare the performance of multivariate GR&R (gage repeatability and reproducibility) studies based on PCA (principal component analysis) and Manova (multivariate analysis of variance) methods. To estimate the multivariate gauge index,
Rogério Santana Peruchi +4 more
doaj +1 more source
Confidence interval based parameter estimation--a new SOCR applet and activity. [PDF]
PLoS ONE, 2011 Many scientific investigations depend on obtaining data-driven, accurate, robust and computationally-tractable parameter estimates. In the face of unavoidable intrinsic variability, there are different algorithmic approaches, prior assumptions and ...
Nicolas Christou, Ivo D Dinov
doaj +1 more source
Weather on Other Worlds. II. Survey Results: Spots Are Ubiquitous on L and T Dwarfs
, 2014 We present results from the "Weather on Other Worlds" Spitzer Exploration Science program to investigate photometric variability in L and T dwarfs, usually attributed to patchy clouds.
Apai, Dániel +9 more
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Computationally efficient permutation-based confidence interval estimation for tail-area FDR
Frontiers in Genetics, 2013 Challenges of satisfying parametric assumptions in genomic settings with thousands or millions of tests have led investigators to combine powerful False Discovery Rate (FDR) approaches with computationally expensive but exact permutation testing.
Joshua eMillstein, Dmitri eVolfson
doaj +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
On the Confidence Intervals in Bioequivalence Studies [PDF]
, 2023 Kexuan Li +3 more
openalex +1 more source