Results 91 to 100 of about 3,080,270 (281)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Confidence with confidence intervals [PDF]

open access: yesBritish Journal of Anaesthesia, 2005
M O, Columb, H E, Thomson
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Robust Neighborhood Confidence Interval and Width to Evaluate the Outcome of a Binary Random Variable of Unequal Cluster Sizes

open access: yesJournal of Biostatistics and Epidemiology
Bachground :While the main advantage of the confidence interval is that it enables more precise evaluations when the risk for the outcome of interest is related to the cluster size, the predicted confidence interval width demonstrates the degree of ...
Tareef Fadhil Raham   +2 more
doaj   +1 more source

Forecasting the Confidence Interval of Efficiency in Fuzzy DEA

open access: yesOperations Research and Decisions, 2021
Data envelopment analysis (DEA) is a well-known method that based on inputs and outputs calculates the efficiency of decision-making units (DMUs). Comparing the efficiency and ranking of DMUs in different periods lets the decision-makers prevent any loss
Azarnoosh Kafi   +2 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

ClimLoco1.0: CLimate variable confidence Interval of Multivariate Linear Observational COnstraint [PDF]

open access: yesGeoscientific Model Development
Projections of future climate are key to society's adaptation and mitigation plans in response to climate change. Numerical climate models provide projections, but the large dispersion between them makes future climate very uncertain.
V. Portmann   +3 more
doaj   +1 more source

HOW CONFIDENT IS THE CONFIDENCE INTERVAL.

open access: yesAnnals of Ibadan postgraduate medicine, 2023
No abstract.
openaire   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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