Results 101 to 110 of about 3,348,916 (301)

The quantile estimation of the maxima of sea levels

open access: yesQuantitative Methods in Economics, 2011
The hydrological modeling has become an intensively studied subject in recent years. One of the most significant problems concerning this issue is to provide the mathematical and statistical tools, which allow to forecast extreme hydrological events ...
Marcin Dudziński, Konrad Furmańczyk
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Calculating and graphing within-subject confidence intervals for ANOVA [PDF]

open access: yes, 2011
The psychological and statistical literature contains several proposals for calculating and plotting confidence intervals for within-subject (repeated measures) ANOVA designs.
Thom Baguley, Baguley, T
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Distinguishing between short and long range dependence: Finite sample properties of rescaled range and modified rescaled range [PDF]

open access: yes
Mostly used estimators of Hurst exponent for detection of long-range dependence are biased by presence of short-range dependence in the underlying time series. We present confidence intervals estimates for rescaled range and modified rescaled range.
Kristoufek, Ladislav
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Confidence interval interpretation: Introducing the confidence interval function

open access: yes, 2022
SVEPM 2022: The Society for Veterinary Epidemiology and Preventive Medicine (SVEPM) Annual Conference 2022, Belfast, Northern Ireland, 23-25 March 2022Confidence intervals are often used incorrectly to perform hypothesis tests in the biomedical sciences.
Messam, Locksley L. McV., Weng, Hsin-Yi
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Forecasting the Confidence Interval of Efficiency in Fuzzy DEA

open access: yesOperations Research and Decisions, 2021
Data envelopment analysis (DEA) is a well-known method that based on inputs and outputs calculates the efficiency of decision-making units (DMUs). Comparing the efficiency and ranking of DMUs in different periods lets the decision-makers prevent any loss
Azarnoosh Kafi   +2 more
doaj  

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