Results 101 to 110 of about 3,080,270 (281)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Confidence Intervals for the Difference and Ratio of Two Variances of Delta–Inverse Gaussian Distributions

open access: yesMathematics
Accurate statistical inference for zero-inflated and highly skewed data requires confidence interval procedures with a strong finite-sample performance.
Wasurat Khumpasee   +2 more
doaj   +1 more source

Sample size estimation for correlations with pre-specified confidence interval [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2014
A common measure of association between two variables x and y is the bivariate Pearson correlation coefficient rho(x,y) that characterizes the strength and direction of any linear relationship between x and y.
Murray Moinester, Ruth Gottfried
doaj  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Device-independent certification of desirable properties with a confidence interval

open access: yesFrontiers in Physics
In the development of quantum technologies, a reliable means for characterizing quantum devices, be it a measurement device, a state-preparation device, or a transformation device, is crucial.
Wan-Guan Chang   +8 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

INTERVALOS DE CONFIANZA PARA EL PARÁMETRO DE LA DISTRIBUCIÓN BINOMIAL INTERVALOS DE CONFIANZA PARA EL PARÁMETRO DE LA DISTRIBUCIÓN BINOMIAL

open access: yesRevista Colombiana de Estadística, 2001
La construcción de intervalos de confianza para la estimación del parámetro π, de la distribución binomial, es un problema importante en el trabajo estadístico aplicado.
Correa M. Juan, Sierra L. Esperanza
doaj  

Technical Efficiency of Australian Wool Production: Point and Confidence Interval Estimates [PDF]

open access: yes
A balanced panel of data is used to estimate technical efficiency, employing a fixed-effects stochastic frontier specification for wool producers in Australia. Both point estimates and confidence intervals for technical efficiency are reported.
Iain Fraser, William C. Horrace
core  

Home - About - Disclaimer - Privacy