Results 111 to 120 of about 1,669,370 (251)

Valid Confidence Intervals and Inference in the Presence of Weak Instruments [PDF]

We investigate confidence intervals and inference for the instrumental variables model with weak instruments. Wald-based confidence intervals perform poorly in that the probability they reject the null is far greater than their nominal size. In the worst
Richard Startz, Eric Zivot, Charles R. Nelson   +2 more
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Median-Unbiased Estimation in DF-GLS Regressions and the PPP Puzzle [PDF]

Using median-unbiased estimation based on Augmented-Dickey-Fuller (ADF) regressions, recent research has questioned the validity of Rogoff's "remarkable consensus" of 3-5 year half-lives of deviations from PPP. The confidence intervals of these half-life
Lopez, C., Murray, C J., Papell, D H.
core   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Confidence intervals for means of positively skewed distributions [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2003
The objective of this study is to compare interval estimation methods for population means of positively skewed distributions. The estimation methods are the interval estimation method with student-t statistics, the interval estimation method with ...
Weerawan Sakdajivacharoen, Teeraporn Verathaworn   +1 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Pointwise Confidence Intervals in Nonparametric Regression with Heteroscedastic Error Structure

, 1997
We assume a nonparametric model with heteroscedastic error structure and consider pointwise confidence intervals for the mean. We construct them by using quantiles from a Cornish-Fisher expansion and from the wild bootstrap distribution, with as well as ...
Neumann, Michael H.
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Exact Confidence Intervals in Distributions with One Parameter

Foundations
The Clopper–Pearson method of constructing a confidence interval for the probability of success in a binary population that follows a Bernoulli distribution is well known.
Xianggui Qu
doaj   +1 more source

Providing Intuition to the Fieller Method with Two Geometric Representations using STATA and Eviews [PDF]

The Fieller Method for the construction of confidence intervals for ratios of the expected value of two normally distributed random variables has been shown by a number of authors to be a superior method to the delta approximation.
J. N. Lye, J.G. Hirschberg
core