Results 41 to 50 of about 2,439,307 (250)
, 2012 Robust design has been widely recognized as a leading method in reducing variability and improving quality. Most of the engineering statistics literature mainly focuses on finding "point estimates" of the optimum operating conditions for robust design ...
Box G. E. P. +5 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
MathematicsDiscrete, finite-state Markov chains are applied in many different fields. When a system is modeled as a discrete, finite-state Markov chain, the asymptotic properties of the system, such as the steady-state distribution, are often estimated based on a ...
Yann Vestring, Javad Tavakoli
doaj +1 more source
Entropy, 2014 System identification, in practice, is carried out by perturbing processes or plants under operation. That is why in many industrial applications a plant-friendly input signal would be preferred for system identification.
Wiktor Jakowluk
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Improved Constraints on D0-D0bar Mixing in D0 -> K+ pi- Decays from the Belle Detector
, 2006 We report the results of a search for D0-D0bar mixing in D0 -> K+ pi- decays based on 400 fb^{-1} of data accumulated by the Belle detector at KEKB. Both assuming CP conservation and allowing for CP violation, we fit the decay-time distribution for the ...
A. Bay +173 more
core +1 more source
Continuous record Laplace-based inference about the break date in structural change models [PDF]
, 2019 Building upon the continuous record asymptotic framework recently introduced by Casini and Perron (2018a) for inference in structural change models, we propose a Laplace-based (Quasi-Bayes) procedure for the construction of the estimate and confidence ...
Casini, Alessandro, Perron, Pierre
core +2 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Convex Relaxations and Approximations of Chance-Constrained AC-OPF Problems
, 2018 This paper deals with the impact of linear approximations for the unknown nonconvex confidence region of chance-constrained AC optimal power flow problems. Such approximations are required for the formulation of tractable chance constraints.
Chatzivasileiadis, Spyros +2 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source