Results 61 to 70 of about 9,117 (218)

ANALYSIS OF FACTORS ASSOCIATED WITH PUBLIC CONFIDENCE IN VACCINATION AGAINST VIRAL HEPATITIS B IN ARKHANGELSK REGION

Журнал инфектологии, 2018
To reveal factors associated with negative attitude to vaccination against viral hepatitis B we performed two crosssectional studies including 1243 adults aged 18–39 years, recruited by a public opinion agency applying a quota sampling method to achieve ...
T. V. Balaeva, E. A. Krieger, O. V. Samodova, A. M. Grjibovski   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Median confidence regions in a nonparametric model

Electronic Journal of Statistics, 2019
The problem of constructing confidence regions for the median in the nonparametric measurement error model (NMEM) is considered. This problem arises in many settings, including inference about the median lifetime of a complex system arising in engineering, reliability, biomedical, and public health settings.
Pena, Edsel A., Kim, Taeho
openaire   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Optimal Confidence Regions for the Multinomial Parameter

CoRR, 2020
Construction of tight confidence regions and intervals is central to statistical inference and decision making. This paper develops new theory showing minimum average volume confidence regions for categorical data. More precisely, consider an empirical distribution $\widehat{\boldsymbol{p}}$ generated from $n$ iid realizations of a random variable that
Matthew L. Malloy, Ardhendu Tripathy, Robert D. Nowak   +2 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

RISK-COMMUNICATION ISSUES IN RADIATION SAFETY: PREFERENCES OF THE PUBLIC IN THE LENINGRAD AND MURMANSK REGIONS ON THE SOURCES OF INFORMATION

Радиационная гигиена, 2018
A survey of the population of the Leningrad and Murmansk regions was conducted in 2016–2017. The survey was devoted to the study of preferred sources of information on radiation safety.
A. M. Biblin, G. A. Arkhangelskaya, S. A. Zelentsova, E. V. Khramtsov, R. R. Akhmatdinov, N. V. Sokolov, V. S. Repin   +6 more
doaj   +1 more source

Confidence regions for filamentary structures

Information and Inference: A Journal of the IMA
Abstract Filamentary structures, also called ridges, generalize the concept of modes of density functions and provide low-dimensional representations of point clouds. Using kernel type plug-in estimators, we give asymptotic confidence regions for filamentary structures based on two bootstrap approaches: multiplier bootstrap and ...
openaire   +2 more sources