Results 121 to 130 of about 1,986,171 (336)

Comparison of family-based association tests in chromosome regions selected by linkage-based confidence intervals [PDF]

open access: diamond, 2005
Juan Pablo Lewinger   +5 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Towards accurate indel calling for oncopanel sequencing through an international pipeline competition at precisionFDA

open access: yesScientific Reports
Accurately calling indels with next-generation sequencing (NGS) data is critical for clinical application. The precisionFDA team collaborated with the U.S.
Binsheng Gong   +17 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Confidence Regions for Steady-State Probabilities and Additive Functionals Based on a Single Sample Path of an Ergodic Markov Chain

open access: yesMathematics
Discrete, finite-state Markov chains are applied in many different fields. When a system is modeled as a discrete, finite-state Markov chain, the asymptotic properties of the system, such as the steady-state distribution, are often estimated based on a ...
Yann Vestring, Javad Tavakoli
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Confidence regions and intervals in nonlinear regression [PDF]

open access: yes, 1997
This lecture presents some methods which we can apply in searching for confidence regions and intervals for true values of regression parameters. The nonlinear regression models with independent and identically distributed errors and L_p norm estimators ...
M. Benšić
core   +1 more source

Honest Confidence Regions for Nonparametric Regression

open access: yesThe Annals of Statistics, 1989
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

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