Results 81 to 90 of about 595,721 (280)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Adaptive Exponential Synchronization of Coupled Complex Networks on General Graphs
We investigate the synchronization in complex dynamical networks, where the coupling configuration corresponds to a weighted graph. An adaptive synchronization method on general coupling configuration graphs is given.
Song Liu +3 more
doaj +1 more source
Irreducible \((v_{3})\) configurations and graphs
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
This paper investigates the application of graph theory and variants of greedy graph coloring algorithms for the optimization of distributed peer-to-peer networks, with a special focus on private blockchain networks.
Miljenko Švarcmajer +3 more
doaj +1 more source
On topological aspects of degree based entropy for two carbon nanosheets
The entropy-based procedures from the configuration of chemical graphs and multifaceted networks, several graph properties have been utilized. For computing, the organizational evidence of organic graphs and multifaceted networks, the graph entropies ...
Manzoor Shazia +3 more
doaj +1 more source
Graph-based system configuration
We present an optimization problem that arises in the context of system-design and the refinement of high-level specifications. We present a graph-based formalization of the problem, thus defining a new optimization problem, which we call MINIMUM CONFIGURATION. We prove MINIMUM CONFIGURATION to be NP-hard and also hard to approximate, i.e. not to be in
openaire +3 more sources
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Local weak convergence and propagation of ergodicity for sparse networks of interacting processes
We study the limiting behavior of interacting particle systems indexed by large sparse graphs, which evolve either according to a discrete time Markov chain or a diffusion, in which particles interact directly only with their nearest neighbors in the ...
Lacker, Daniel +2 more
core
Self-Dual Configurations and Their Levi Graphs [PDF]
Introduction. By a configuration we shall mean a set of points and straight lines (or planes) between which certain well-determined incidences exist. These configurations are not necessarily regular, that is, we shall not suppose every line (plane) to be incident with the same number of configuration points, and dually, different points of the ...
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