Results 51 to 60 of about 256,836 (264)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
BPHZ renormalization in configuration space for the A4-model
Recent developments for BPHZ renormalization performed in configuration space are reviewed and applied to the model of a scalar quantum field with quartic self-interaction.
Steffen Pottel
doaj +1 more source
Mod p truncated configuration spaces
The author studies the space \(E^{d}_{J}(X)\) of configurations of ordered \(n\)-tuples of unordered \(d\)-tuples of points in \(X\). The n-tuples satisfy a set of intersection conditions specified by \(J\). For example one result asserts the natural homotopy equivalence of \(\lim_{d\to \infty}E^{d}_{J}(\mathbb{R}^k)\) and \(\Omega_{0}^{k}\bigcup_{d ...
openaire +3 more sources
Wasserstein Distance on Configuration Space [PDF]
We investigate here the optimal transportation problem on configuration space for the quadratic cost. It is shown that, as usual, provided that the corresponding Wasserstein is finite, there exists one unique optimal measure and that this measure is supported by the graph of the derivative (in the sense of the Malliavin calculus) of a ``concave'' (in a
openaire +3 more sources
Configuration Spaces of Mechanical Linkages [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jordan, D., Steiner, M.
openaire +2 more sources
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Equilibrium stochastic dynamics of Poisson cluster ensembles
The distribution μ of a Poisson cluster process in Χ=Rd (with n-point clusters) is studied via the projection of an auxiliary Poisson measure in the space of configurations in Χn, with the intensity measure being the convolution of the background ...
L.Bogachev, A.Daletskii
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Quantum Space behind Simple Quantum Mechanics
In physics, experiments ultimately inform us about what constitutes a good theoretical model of any physical concept: physical space should be no exception.
Chuan Sheng Chew +2 more
doaj +1 more source

