Results 101 to 110 of about 519,225 (355)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Dividing and setting strategy of improving calculation efficiency for needle electrode corona discharge with a large‐scale space

High Voltage, 2022
Needle electrodes are widely used in the research of corona discharge. Aiming at the problem of needle electrode discharge in a large‐scale space (tens or even hundreds of centimetres), a hybrid model was proposed in the previous work.
Dingchen Li, Chuan Li, Jiawei Li, Pengyu Wang, Zhi Liu, Wendi Yang, Ming Zhang, Yong Yang, Kexun Yu   +8 more
doaj   +1 more source

Confinement-Controlled Water Engenders Unusually High Electrochemical Capacitance

, 2023
The electrodynamics of nanoconfined water have been shown to change dramatically compared to bulk water, opening room for safe electrochemical systems.
Alexander Ryzhov (9673077), Svetlana Melnik, Keith J. Stevenson (1287621), Aleksandra Radenovic, Svetlana Melnik (16556966), Alexei Kiselev (5570618), Alexander Ryzhov, Keith J. Stevenson, Tanja Weil, Alexei Kiselev, Vasily G. Artemov, Aleksandra Radenovic (213528), Tanja Weil (1326315), Vasily G. Artemov (9673074)   +13 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Experimental and numerical modeling of plasma start-up assisted by electron drift injection on J-TEXT

Nuclear Fusion, 2023
Start-up is one of the critical phases for tokamak discharge. The electron drift injection (EDI) system has been developed on J-TEXT for start-up studies.
Junli Zhang, Zhifeng Cheng, Yanli Peng, Zhoujun Yang, Kazunobu Nagasaki, Nengchao Wang, Hao Cai, Yonghua Ding, Zhipeng Chen, Zhongyong Chen, Wei Jiang, Donghui Xia, Zhijiang Wang, Yuan Pan, J-TEXT team   +14 more
doaj   +1 more source

Vortices and Confinement

, 2000
12 pages, LaTeX file, 2 epsf figures. Contribution to the Proceedings of the workshop ``Lattice fermions and the structure of the vacuum'', 5-9 October 1999, Dubna ...
Kovács, T. G., Tomboulis, E. T.
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Ductility enhancement of geopolymer concrete columns using FRP confinement [PDF]

, 2016
Geopolymer concrete is an environmentally friendly, green construction material. However its use is constrained by its increased brittleness and lack of understanding of its behaviour under multi-axial loadings.
Lokuge, Weena, Karunasena, Warna
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Infernal instabilities in negative-triangularity plasmas with negative central shear

Nuclear Fusion
A systematic numerical investigation is carried out to understand magnetohydrodynamic stability of the ideal infernal-kink instability in tokamak plasmas with both negative triangularity (neg-D) shaping and negative central shear for the equilibrium ...
X.M. Zhang, L. Li, Y.Q. Liu, Z.Y. Dong, J.W. Li, Y. Liang, F.C. Zhong   +6 more
doaj   +1 more source