Results 91 to 100 of about 736,721 (340)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

Magnetic-island induced geometric stabilization of turbulence triggering eITB bifurcation

open access: yesNuclear Fusion
We demonstrate that geometric deformation of flux-surface induced by a magnetic island can trigger the bifurcation to an electron internal transport barrier (eITB) through a novel positive feedback loop arising from the nonlinear coupling between the ...
Zhangsheng Huang   +3 more
doaj   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

SOLPS-ITER modeling of neon-seeded EAST plasmas under connected double-null configurations and its impact on tungsten impurity behaviors

open access: yesNuclear Fusion
The SOLPS-ITER edge modeling package was employed to numerically investigate neon (Ne)-seeded EAST plasmas under connected-double-null configurations, focusing on Ne impurity transport and its impacts on tungsten (W) impurity behaviors.
Fuqiong Wang   +9 more
doaj   +1 more source

Curvature-induced singularities and stability analysis of curved perfectly matched layers for ICRF antenna–plasma coupling

open access: yesNuclear Engineering and Technology
In electromagnetic modeling of ion cyclotron range of frequencies (ICRF) antennas, curved coupling models provide a more realistic representation of the antenna and edge-plasma geometry, improving the accuracy of wave-coupling and loading predictions ...
Wentao Geng   +4 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

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