Results 71 to 80 of about 736,721 (340)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Infernal instabilities in negative-triangularity plasmas with negative central shear

Nuclear Fusion
A systematic numerical investigation is carried out to understand magnetohydrodynamic stability of the ideal infernal-kink instability in tokamak plasmas with both negative triangularity (neg-D) shaping and negative central shear for the equilibrium ...
X.M. Zhang, L. Li, Y.Q. Liu, Z.Y. Dong, J.W. Li, Y. Liang, F.C. Zhong   +6 more
doaj   +1 more source

Confinement as crossover [PDF]

, 2000
The order parameter of confinement together with the haaron model of the QCD vacuum is reviewed and it is pointed out that confining forces are generated by the non-renormalizable, invariant Haar-measure vertices of the path integral.
Polonyi, Janos
core   +2 more sources

Confinement in QCD

, 1999
The guiding lines of lattice investigations on colour confinement are reviewed, together with recent results.Comment: 7 pages,3 figures, Plenary talk at PANIC'99,10-16 June 1999 ...
A. Di Giacomo, Alles, Creutz, Di Cecio, Di Giacomo, Di Giacomo, Di Giacomo, Di Vecchia, Englert, Fringberg, Fröhlich, Fukugita, Haymaker, Kadanoff, Mandelstam, Marino, Müller, Okun, Polyakov, Seiberg, Veneziano, Weinberg, Weinberg, Wilson, Witten, Witten, ’t Hooft, ’t Hooft, ’t Hooft, ’t Hooft   +29 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Topology and confinement

, 2009
These lectures contain an introduction to instantons, calorons and dyons of the Yang--Mills gauge theory. Since we are interested in the mechanism of confinement and of the deconfinement phase transition at some critical temperature, the Yang--Mills ...
't Hooft, Atiyah, Atiyah, Belavin, Berezin, Bernard, Bogomolny, Bruckmann, Bruckmann, Bruckmann, Chu, Cossu, Danzer, Davies, Davies, Del Debbio, Diakonov, Diakonov, Diakonov, Diakonov, Diakonov, Diakonov, Diakonov, Diakonov, Dmitri Diakonov, Douglas, Faddeev, Gibbons, Gibbons, Greensite, Gross, Hanany, Harrington, Jackiw, Kraan, Kraan, Kraan, Lee, Lee, Lee, Lucini, Lucini, Lucini, Negele, Pepe, Polyakov, Prasad, Shifman, Slizovskiy, Smilga, Unsal, Weiss   +51 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Long Range Magnetic Order and the Darwin Lagrangian

, 1999
We simulate a finite system of $N$ confined electrons with inclusion of the Darwin magnetic interaction in two- and three-dimensions. The lowest energy states are located using the steepest descent quenching adapted for velocity dependent potentials ...
A. Compagner, A.N. Kaufman, C.G. Darwin, C.W. Nielson, D. Ruelle, D.H.E. Dubin, D.Q. Ding, E. Hairer, G. Breit, G. Breit, H. Essen, H. Essen, H. Essen, H. Essen, H.A. Posch, J. De Luca, J. De Luca, J. De Luca, J. De Luca, J. Krizan, J.D. Jackson, J.H. Van Vleck, J.L. Anderson, Jayme De Luca, K.E. Brenan, L. Candido, L. Page, M. Antoni, M.P. Allen, R. Neiden Hill, R.N. Hill, S. Ichimaru, V.I. Arnold, V.M. Bedanov, Vishal Mehra, W. Appel, W. Thirring   +36 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Bifurcation from L-mode to internal transport barrier triggered by a magnetic island in tokamak plasmas

Nuclear Fusion
Magnetic islands are believed to be responsible for triggering the internal transport barrier (ITB) around the rational surface and hence improves confinement in magnetic confinement fusion plasma, for more than two decades.
Feiyue Mao, Nengchao Wang, Katsumi Ida, Chuanxu Zhao, Qinlin Tao, Yangbo Li, Zhengkang Ren, Zijian Xuan, Ruomu Wang, Jiangang Fang, Xixuan Chen, Haonan Fang, Hanhui Li, Song Zhou, Wei Yan, Zhoujun Yang, Donghui Xia, Zhongyong Chen, Lu Wang, Yonghua Ding, the J-TEXT Team   +20 more
doaj   +1 more source