Results 71 to 80 of about 177,629 (318)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Bifurcation from L-mode to internal transport barrier triggered by a magnetic island in tokamak plasmas

Nuclear Fusion
Magnetic islands are believed to be responsible for triggering the internal transport barrier (ITB) around the rational surface and hence improves confinement in magnetic confinement fusion plasma, for more than two decades.
Feiyue Mao, Nengchao Wang, Katsumi Ida, Chuanxu Zhao, Qinlin Tao, Yangbo Li, Zhengkang Ren, Zijian Xuan, Ruomu Wang, Jiangang Fang, Xixuan Chen, Haonan Fang, Hanhui Li, Song Zhou, Wei Yan, Zhoujun Yang, Donghui Xia, Zhongyong Chen, Lu Wang, Yonghua Ding, the J-TEXT Team   +20 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

High-beta disruption prediction study on HL-2A with instance-based transfer learning

Nuclear Fusion
Unmitigated disruptions pose a much more serious threat when large-scale tokamaks are operating in the high performance regime. Machine learning based disruption predictors can exhibit impressive performance.
Y. Zhong, W. Zheng, Z.Y. Chen, W. Yan, F. Xia, L.M. Yu, F.M. Xue, C.S. Shen, X.K. Ai, Z.Y. Yang, Y.L. Yu, Z.S. Nie, Y.H. Ding, Y.F. Liang, Z.P. Chen, J-TEXT Team   +15 more
doaj   +1 more source

Replication Dataset for "The Unintended Consequences of Confinement: Evidence From the Rural Area in Guatemala"

, 2022
International Food Policy Research Institute
openalex   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The Marion Experiment: Long-term Solitary Confinement and the Supermax Movement edited by Stephen C. Richards. Carbondale (IL): Southern Illinois University Press (2015) 336 pp.

, 2023
Ph. David
openalex   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Magnetic-island induced geometric stabilization of turbulence triggering eITB bifurcation

Nuclear Fusion
We demonstrate that geometric deformation of flux-surface induced by a magnetic island can trigger the bifurcation to an electron internal transport barrier (eITB) through a novel positive feedback loop arising from the nonlinear coupling between the ...
Zhangsheng Huang, Nengchao Wang, Weixin Guo, Lu Wang   +3 more
doaj   +1 more source