Results 51 to 60 of about 283,799 (295)

Control of stochasticity in magnetic field lines [PDF]

open access: yes, 2005
We present a method of control which is able to create barriers to magnetic field line diffusion by a small modification of the magnetic perturbation. This method of control is based on a localized control of chaos in Hamiltonian systems.
Chandre, Cristel   +4 more
core   +6 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Ultra-Low-Loss Hollow-Core Bragg Antiresonant Fiber With Super Bandwidth Transmission Window

open access: yesIEEE Photonics Journal, 2022
A novel hollow-core antiresonant fiber with a Bragg structure is proposed. It is numerically simulated using a commercial finite element method, and optical properties of the fiber, such as mode field, confinement loss, and bend loss, are numerically ...
Changming Xia   +9 more
doaj   +1 more source

High Energy Electron Confinement in a Magnetic Cusp Configuration

open access: yes, 2014
We report experimental results validating the concept that plasma confinement is enhanced in a magnetic cusp configuration when beta (plasma pressure/magnetic field pressure) is order of unity.
Alderson, Eric   +8 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Neutron time-of-flight measurements of charged-particle energy loss in inertial confinement fusion plasmas [PDF]

open access: yes, 2019
Neutron spectra from secondary ^{3}H(d,n)α reactions produced by an implosion of a deuterium-gas capsule at the National Ignition Facility have been measured with order-of-magnitude improvements in statistics and resolution over past experiments.
Caggiano, J. A.   +27 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Photonic Crystal Fiber–Based Surface Plasmon Resonance Sensor for Precise Biochemical Refractive Index Sensing

open access: yesPhotonics
In this work, a D-shaped Photonic Crystal Fiber (PCF) sensor with a detection range of 1.30–1.35 is proposed, including Gold (Au), Titanium Dioxide (TiO2), graphene, and a functionalized sensing region.
Lalit Garia   +3 more
doaj   +1 more source

Near-Field Emission of Lead-Sulfide-Selenide Homojunction Lasers [PDF]

open access: yes, 1980
Measurements of the near-field intensity distributions of three lead-sulfide-selenide diode lasers operating near 4.8 μm have been made as a function of injection current.
Kimble, H. J.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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