Results 61 to 70 of about 283,799 (295)

Azimuthal Fourier decomposition for loss analysis of hollow-core tube lattice fibers, Part II: Tube thickness variation effects

Results in Optics
The effect on confinement loss of thickness variations along the perimeter of the tubes composing the cladding of inhibited-coupling guiding Tube Lattice hollow-core fibers is investigated by using the Azimuthal Fourier Decomposition technique (developed
Federico Melli, Fabio Giovanardi, Kostiantyn Vasko, Lorenzo Rosa, Fetah Benabid, Luca Vincetti   +5 more
doaj   +1 more source

Signals of confinement in Green functions of SU(2) Yang-Mills theory

, 2004
The vortex picture of confinement is employed to explore the signals of confinement in Yang-Mills Green functions. By using SU(2) lattice gauge theory, it has been well established that the removal of the center vortices from the lattice configurations ...
A. Cucchieri, C. D. Roberts, D. Zwanziger, D. U. Jungnickel, Hugo Reinhardt, J. C. Taylor, J. C. R. Bloch, Jochen Gattnar, K. Langfeld, Kurt Langfeld, M. Engelhardt, M. Engelhardt, T. Kugo, V. N. Gribov   +13 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hybrid structure hollow-core anti-resonant fiber with low confinement loss at 1550 nm and high birefringence in the C-band

Results in Physics
This study proposes a hollow-core anti-resonant fiber with a hybrid nested cladding structure, aimed at achieving high birefringence, broad bandwidth, and low confinement loss. The proposed fiber has a three-layer nested ring structure in the x-direction
Yuan Yang, Hongxiang Xu, Xuhang Li, Zhiyong Ren, Zhiyun Hou, Jiantao Liu, Changmin Xia, Guiyao Zhou   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Design and Analysis of a Photonic Crystal Fiber Sensor for Identifying the Terahertz Fingerprints of Water Pollutants

Photonics
Ensuring the purity of water sources is a paramount global challenge, necessitating the development of highly sensitive and rapid detection technologies.
Sajjad Mortazavi, Somayeh Makouei, Karim Abbasian, Sebelan Danishvar   +3 more
doaj   +1 more source

Circulator based on spoof surface plasmon polaritons

, 2016
Circulators based on spoof surface plasmon polaritons are designed and analyzed. In the letter, we use blade structure to realize the propagation of SSPPs wave and a matching transition is used to feed energy from coplanar waveguide to the SSPPs. And the
Li, Yongfeng, Qiu, Tianshuo, Qu, Shaobo, Wang, Jiafu   +3 more
core   +1 more source