Results 111 to 120 of about 131,723 (308)

Mechanical pressure and momentum conservation in dry active matter

open access: yes, 2017
We relate the breakdown of equations of states for the mechanical pressure of generic dry active systems to the lack of momentum conservation in such systems. We show how sources and sinks of momentum arise generically close to confining walls.
Fily, Yaouen   +4 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The environments of double radiogalaxies [PDF]

open access: yes
Discussed here are simple methods by which the densities and pressures of the gas confining double radiogalaxies can be estimated from optical and x ray data.
Rawlings, Steve
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Experimental Study on Radial Cementation Strength of the First Cementing Interface in HTHP Wells

open access: yesShiyou jixie, 2021
In view of the stress status of cement ring in high-temperature and high-temperature(HTHP)wells, a set of full-size HTHP cement ring sealing integrity evaluation test equipment was developed. The influence of confining pressure and casing pressure on the
Huang Peng   +4 more
doaj  

Leak detector [PDF]

open access: yes, 1975
A detector for sensing a leaking of fluid pressures is reported. The detector is characterized by an hermetically sealed housing confining therewithin a first normalized pressure, a connector for coupling the housing in direct communication with a ...
Sawyer, J. T.
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Effect of Confining Pressure, Relative Density and Shear Strain on the Poisson’s Ratio of Clean Sand [PDF]

open access: yes, 2015
In comparison to other dynamic properties of soil, Poisson’s ratio is mostly considered as an elasti c constant. The effect of different para meters on the Poisson’s ratio of soil is neglected in most of the ...
Dutta, T T, Saride, Sireesh
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Effect of confining pressure on mechanical behavior of methane hydrate-bearing sediments

open access: yesPetroleum Exploration and Development, 2011
Synthesized gas hydrate in lab was mixed with kaoline to form core samples, so as to simulate the hydrate-bearing sedimentary layers in the seabed. Under conditions of different confining pressure, triaxial compressive tests were conducted on hydrate ...
Yanghui Li   +4 more
doaj   +1 more source

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