Results 141 to 150 of about 4,596,099 (356)

Cyclic confining pressure and rock permeability: Mechanical compaction or fines migration. [PDF]

open access: yesHeliyon, 2023
Kozhevnikov EV   +4 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Dissipated energy in undrained cyclic triaxial tests [PDF]

open access: yes, 2015
Energy-based methods are an emerging tool for the evaluation of liquefaction potential. These methods relate excess pore water pressure build-up to seismic energy dissipated per unit volume.
Azeiteiro, RJN   +3 more
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Numerical study on the shear strength of granular materials under the low confining pressure

open access: yesSoils and Foundations
The relationship between stress and strength in granular soil differs under low confining pressure as compared to high confining pressure, which is of great importance for the geotechnical engineering. Numerical simulations using discrete element method (
Daosheng Ling   +5 more
doaj   +1 more source

Pressure-dependent flow behavior of Zr_(41.2)Ti_(13.8)Cu_(12.5)Ni_(10)Be_(22.5) bulk metallic glass [PDF]

open access: yes, 2003
An experimental study of the inelastic deformation of bulk metallic glass Zr_(41.2)Ti_(13.8)Cu_(12.5)Ni_(10)Be_(22.5) under multiaxial compression using a confining sleeve technique is presented. In contrast to the catastrophic shear failure (brittle) in
Lu, Jun, Ravichandran, Guruswami
core  

Effects of confining pressure on acoustic emission and failure characteristics of sandstone

open access: yesInternational Journal of Mining Science and Technology, 2021
Zhen Huang   +6 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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