Results 151 to 160 of about 16,352 (264)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Strength of artificially frozen sand with low confining pressure under a three-dimensional stress path. [PDF]

Sci Rep
Yao Z, Xu X, Liu S.
europepmc   +1 more source

Creep and permeability evolution behavior of red sandstone containing a single fissure under a confining pressure of 30 MPa. [PDF]

Sci Rep, 2020
Yang SQ, Hu B.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Study on a Creep Constitutive Model of Phyllite Considering the Coupling Factors of Bedding, Confining Pressure, and Water Saturation. [PDF]

ACS Omega
Wu Y, Hu J, Yang D, Wen G.
europepmc   +1 more source

Innovative Apparatus for Testing Filtration, Sorption and CO₂/CH₄ Exchange Sorption Processes Under Isobaric Conditions on Sorbent Subjected to Confining Pressure in Terms of Laboratory Tests of CO₂-ECBM Technology. [PDF]

Sensors (Basel), 2020
Kudasik M, Skoczylas N, Pajdak A.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Growth of nonmotile stress-responsive bacteria in 3D colonies under confining pressure. [PDF]

Biophys J
Rahbar S, Mohammad-Rafiee F, Santen L, Shaebani R.   +3 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Synergistic effects of crystal habit and confining pressure on the compressive mechanical behavior of crystalline rock: a grain-based modeling analysis. [PDF]

Sci Rep
Zhan Z, Wang J, Du J, Wang B, Yang Z, Huang X.   +5 more
europepmc   +1 more source