Results 141 to 150 of about 23,904 (309)

Parameter kekuatan tanah berdasarkan triaxial compression dengan confining pressure berkurang

open access: yes, 2005
Selama ini dalam penggalian dan pengurugan tanah, orang selalu berpedoman pada kohesi (c) dan sudut geser dalam (o) yang didapat dari Triaxial Tes dengan tegangan aksial bertambah dan tegangan radial konstan sampai tanah sampel tersebut runtuh.
Hosen, Denny, Rompies, Frederik A
core  

Experimental Study of the Laws Between the Effective Confining Pressure and Mudstone Permeability

open access: yes, 2014
The stress dependent permeability of a mudstone sample was measured using a transient pulse technique in a specially designed apparatus in which the confining pressure, pore pressure, and temperature were independently controlled.
Zhiming, FANG   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Coupling effects of confining pressure and strain rate on rock compressive strength

open access: yes
This study systematically investigated the coupling effects of confining pressure and strain rate on the dynamic strength of granite through dynamic triaxial compression tests.
Haibo Li   +5 more
core   +1 more source

Numerical study on the shear strength of granular materials under the low confining pressure

open access: yesSoils and Foundations
The relationship between stress and strength in granular soil differs under low confining pressure as compared to high confining pressure, which is of great importance for the geotechnical engineering. Numerical simulations using discrete element method (
Daosheng Ling   +5 more
doaj   +1 more source

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