Results 101 to 110 of about 1,948,384 (297)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
High Confirmation and Inductive Validity
Studies in Logic, Grammar and Rhetoric, 2016 Does a high degree of confirmation make an inductive argument valid? I will argue that it depends on the kind of question to which the argument is meant to be providing an answer.
Botting David
doaj +1 more source
Emergence and Evidence: A Close Look at Bunge’s Philosophy of Medicine
Philosophies, 2019 In his book “Medical Philosophy: Conceptual issues in Medicine”, Mario Bunge provides a unique account of medical philosophy that is deeply rooted in a realist ontology he calls “systemism”.
Rainer J. Klement +1 more
doaj +1 more source
, 2010 This paper offers sequential-interactional and prosodic observations on the confirmation forms ja hoor / nee hoor ('yes'+particle hoor / 'no' + hoor) in Dutch talk-in-interaction, as part of a larger analysis of the form and function of the particle hoor.
Mazeland, H, Plug, L
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Views on Spirituality in Old Age: What Does Love Have to Do with It?
Religions, 2018 This paper addresses the importance of providing spiritual care for older people within the context of nursing. Based on the author’s doctoral thesis, the importance of love in relation to spirituality and spiritual care will be discussed herein ...
Linda Rykkje
doaj +1 more source
Observational confirmation of the Sun's CNO cycle
, 2006 Gamma rays from a solar flare in Active Region 10039 on 23 July 2002 with the RHESSI spacecraft spectrometer indicate that the CNO cycle occurs at the solar surface, in electrical discharges along closed magnetic loops.
Manuel, O. +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Binus Business ReviewFinancial service innovation is increasingly developing with the massive growth in the use of Information and Communication Technology (ICT). Paylater is a digital financial service product that has recently developed rapidly.
Freddy Pandapotan Simbolon +1 more
doaj +1 more source