Results 101 to 110 of about 904,974 (305)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
High Confirmation and Inductive Validity
Studies in Logic, Grammar and Rhetoric, 2016 Does a high degree of confirmation make an inductive argument valid? I will argue that it depends on the kind of question to which the argument is meant to be providing an answer.
Botting David
doaj +1 more source
Confirmation Class of Immanuel Lutheran Church in Missoula, Montana
, 2013 This image shows the May 24, 1931 Confirmation Class of Immanuel Lutheran Church in Missoula, Montana. Shown (l-r) are Rev.
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Confirmation Class of Bethel Lutheran Church, Little Falls, Minnesota
, 2013 This image shows the November 2, 1947 Confirmation Class of Bethel Lutheran Church, Little Falls, Minnesota. Shown standing (l-r): Carol Ann Hanson, Clayton Carlson, Dale H. Lindquist, Edward Peterson, and Nancy Lou Olson. Seated: Rev.
core +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Information, confirmation, and conditionals
Journal of Applied Logic, 2014 Loosely speaking, a proposition adds the more information to corpus b, the greater the proportion of possibilities left open by b that it rules out. Plausible qualitative constraints lead to the result that any measure of information-added is a strictly decreasing rescaling of a conditional probability function sending 1 to 0.
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source