Results 81 to 90 of about 904,974 (305)

Carnap-Confirmation, Content-Cutting, & Real Confirmation

open access: yes, 2007
Since Carnap's notion of confirmation as probabilistic favorable relevance violates the intuitive Hempelian transmittability condition that confirmation of a hypothesis be transmitted to all the content of the hypothesis it cannot capture some key ...
Gemes, Ken
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

How Large Must an Associational Mean Difference Be to Support a Causal Effect?

open access: yesMethodology
An observational study might support a causal claim if the association found cannot be explained by bias due to unconsidered confounders. This bias depends on how strongly the common predisposition, a summary of unconsidered confounders, is related to ...
Michael Höfler   +2 more
doaj   +1 more source

An interview with Kenneth Aizawa

open access: yesThe Reasoner
Hykel Hosni interviews Kenneth Aizawa, Professor of Philosophy of Science at Rutgers University, Newark. The interview opens with Aizawa’s reflections on the challenges currently confronting U.S. universities under the second Trump administration.
Hykel Hosni
doaj   +1 more source

How Strong is the Confirmation of a Hypothesis by Significant Data? [PDF]

open access: yes, 2013
The aim of the article is to determine how much a hypothesis H is actually confirmed if it has successfully passed a classical significance test. Bayesians have already raised many serious objections against significance testing, but in doing so they ...
Bartelborth, Thomas
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Disconfirmation is not modus tollens

open access: yesThe Reasoner
Scientific disconfirmation has often been thought to be reasoning by modus tollens. This interpretation, however, misconstrues the conditionals in this scientific reasoning in terms of the material conditional, rather than in terms of causal ...
Kenneth Aizawa
doaj   +1 more source

Determinants of Tourism Satisfaction in the Cultural and Heritage Sector of Dar es Salaam, Tanzania [PDF]

open access: yesInternational Journal of Management, Accounting and Economics
This paper presents the findings of a study that assessed the determinants of tourism satisfaction in the cultural and heritage sector of Dar es Salaam, Tanzania.
Felix Chille, Deograthias Dafi
doaj   +1 more source

Dundee Discussion Papers in Economics 158:Is positive confirmation relevant for game theory?: an experimental test [PDF]

open access: yes, 2003
Previous experimental work has found that Positive Confirmation is a significant factor in learning. However, to date, there has been no attempt to test this phenomenon in a game- theoretic setting.
Jones, Martin K.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy