Results 71 to 80 of about 170,218 (202)

A New Measure for the Tendency to Select Ideologically Congruent Political Information: Scale Development and Validation

International Journal of Communication, 2016
Selective exposure is a popular research construct, but the strategies used to operationalize ideologically congruent exposure in contemporary correlational research are problematic.
Yariv Tsfati
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Reverse spin bias: preliminary observations of reporting bias in medical systematic reviews

Research Integrity and Peer Review
Background While conducting an umbrella review of e-cigarettes for smoking cessation, we observed that in many instances, systematic review authors reported findings favorable to the treatment, yet they declined to recommend it or recommended against it ...
Renée O’Leary, Giusy Rita Maria La Rosa, Riccardo Polosa   +2 more
doaj   +1 more source

The Politics of Ethics: Can Honesty Cross Over Political Polarization?

Journalism and Media
This research demonstrates how confirmation and disconfirmation biases manifest based on individuals’ political affiliations when processing a self-disclosure message in the context of a political crisis. An experiment presented a crisis message in which
Sang Lee, Samar Ben Romdhane
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Selective information sampling: Cognitive coherence in evaluation of a novel item

Judgment and Decision Making, 2009
This study investigates the amount and valence of information selected during single item evaluation. One hundred and thirty-five participants evaluated a cell phone by reading hypothetical customers reports. Some participants were first asked to provide
Peter A. F. Fraser-Mackenzie, Itiel E. Dror   +1 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Confirmation Bias Analysis of Religious Intolerance Trends: A Study of the Views of Lecturers at Religious-Based Universities in Yogyakarta

Gema Teologika
Abstrak Penelitian ini bertujuan untuk menganalisis peran Bias Konfirmasi dalam menentukan sikap dan perilaku intoleransi beragama menurut dosen universitas agama di Yogyakarta.
Endah Setyowati, Hendra Sigalingging
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source