Results 101 to 110 of about 8,004,320 (260)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Fit indices for confirmatory factor analyses of the models tested (W1).

, 2018
Fit indices for confirmatory factor analyses of the models tested (W1).
Oskari Lahtinen (6053969), Tiina Turunen (6053972), Christina Salmivalli (789257), Sonja Kumlander (6053966)   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Psychometric validation of the WHO-5 and WHO-4 well-being index scales for assessing psychological well-being and detecting depression in Japanese school-aged children: a community-based study

Frontiers in Public Health
IntroductionThe 5-item World Health Organization Well-Being Index (WHO-5) is widely used to assess psychological well-being, but its psychometric properties in younger populations, particularly in non-Western settings, remain underexplored.
Masaki Adachi, Masaki Adachi, Masaki Adachi, Michio Takahashi, Michio Takahashi, Michio Takahashi, Hiroyuki Mori, Hiroyuki Mori, Tomoko Nishimura, Tomoko Nishimura, Makoto Osada, Minami Adachi, Rei Monden, Manabu Wakuta, Kazuhiko Nakamura   +14 more
doaj   +1 more source

Validation and invariance across gender of the Beliefs About Appearance Scale (BAAS) in a community sample of heterosexual adults in a committed relationship

Trends in Psychiatry and Psychotherapy, 2018
Objective To evaluate the psychometric properties of the Beliefs About Appearance Scale (BAAS) in terms of its factorial structure and invariance, reliability, and validity when applied to adults from the community. Methods Participants consisted of 810
Patrícia M. Pascoal, Maria-João Alvarez, Magda Sofia Roberto   +2 more
doaj   +1 more source

Factor loadings and path loadings estimated by exploratory and confirmatory factor analyses for the Social Networking Activity Intensity Scale (SNAIS).

, 2016
Factor loadings and path loadings estimated by exploratory and confirmatory factor analyses for the Social Networking Activity Intensity Scale (SNAIS).
Zuguo Qin (3308493), Xuefen Su (2063731), Phoenix K. H. Mo (398414), Joseph T. F. Lau (293209), Jie Tang (46802), Anise M. S. Wu (693230), Jibin Li (594654)   +6 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Initial validation of scales measuring trust and attitudes toward (educational) science in Belgium

Frontiers in Education
IntroductionThis study is part of a broader effort to validate psychometric scales translated and adapted to the French-speaking Belgian teacher education context. It examines the factor structure and internal consistency of several instruments measuring
Eva Gonzalez-Vargas, Remy Decorte, Antoine Derobertmasure, Dylan Dachet   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Exploratory factor and confirmatory analyses of the polycystic ovary syndrome health-related quality of life questionnaire (PCOSQ-50)

Health and Quality of Life Outcomes
Background A condition-specific instrument is necessary to measure the health-related quality of life among those with polycystic ovary syndrome (PCOS), the most common chronic endocrinopathy among women.
Pamela J. Wright, Abbas S. Tavakoli, Robin M. Dawson   +2 more
doaj   +1 more source