Results 101 to 110 of about 8,911,577 (322)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Model fit statistics from the confirmatory factor analyses.
Model fit statistics from the confirmatory factor analyses.
Hirokazu Osada (7256201) +6 more
core +1 more source
BackgroundDementia is a life-limiting condition that is increasing in global prevalence in line with population ageing. In this context, it is necessary to accurately measure dementia knowledge across a spectrum of health professional and lay populations
Michael J. Annear +5 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Results from confirmatory factor analyses in study 1.
Results from confirmatory factor analyses in study 1.
Joeri Hofmans (631700) +4 more
core +1 more source
This study examined the factorial validity of the Slovene version of the cultural intelligence scale (CQS) in a representative sample of 1,000 Slovenian participants (49% were female).
Eva Boštjančič +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A confirmatory factor analysis of two models of sensation seeking.
The factor structures of Zuckerman's sensation seeking scale Form V (SSSV) [Zuckerman, M., Eysenck, S. & Eysenck, H. J. (1978). Sensation seeking in England and America: cross-cultural, age and sex comparisons.
Haynes, Caroline. A. +3 more
core
IntroductionThe 5-item World Health Organization Well-Being Index (WHO-5) is widely used to assess psychological well-being, but its psychometric properties in younger populations, particularly in non-Western settings, remain underexplored.
Masaki Adachi +14 more
doaj +1 more source

