Results 231 to 240 of about 8,004,320 (260)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Cross-Cultural Adaptation and Validation of the Academic Resilience Scale-30 for Responses to Adverse Workplace Performance Evaluation Among Greek Public Healthcare Employees. [PDF]

Healthcare (Basel)
Kapritsou M, Papanikolaou V, Nikos M, Sergentanis TN.   +3 more
europepmc   +1 more source

Validation of the AI mental health Therapy Attitude, Perception, and Intention Scale (AiTAPI). [PDF]

Internet Interv
Lam LT, Lam MK.
europepmc   +1 more source

Cross-Cultural Adaptation and Psychometric Evaluation of the Turkish DESTEK (D-SCOPE) Questionnaire: A Multidimensional Assessment of Dietitians' Knowledge, Attitudes and Preparedness Regarding Dietary Supplements in Türkiye. [PDF]

J Hum Nutr Diet
Bilen AB, Çalık A, Demiray PE, Kandemir K, Kalkan GE, Turan Ö, Alphan ME.   +6 more
europepmc   +1 more source